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BioWorld - Tuesday, February 24, 2026
Home » Topics » Antibody, BioWorld Science

Antibody, BioWorld Science
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Gastrointestinal

Abbvie licenses Futuregen’s next-generation TL1A antibody for inflammatory bowel disease

June 14, 2024
Abbvie Inc. and Futuregen Biopharmaceutical (Beijing) Co. Ltd. have signed a license agreement to develop FG-M701, a next-generation TL1A antibody for the treatment of inflammatory bowel disease.
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AI-generated image for cancer cells observed under a microscope
Immuno-oncology

Shaperon signs MOU with Dong-A ST to accelerate development of nanobody-based drugs

June 11, 2024
Hudson Therapeutics Inc., a U.S. subsidiary of Shaperon Inc., has announced the signing of a memorandum of understanding (MOU) between Shaperon and Dong-A ST Co. Ltd. for the development of nanobody-based new drugs.
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Parkinson's disease illustration showing neurons containing alpha-synuclein
Neurology/psychiatric

Alchemab secures grant for antibodies targeting prostaglandin biology in Parkinson’s

June 6, 2024
Alchemab Therapeutics Ltd. has been awarded a grant of $595,000 by The Michael J. Fox Foundation for Parkinson’s Research (MJFF) to support its Parkinson’s disease program.
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Antibodies attacking SARS-CoV-2 virus
Infection

Exevir’s XVR-013m demonstrates neutralization potency against SARS-CoV-2 variant JN.1

June 5, 2024
Exevir Bio BV has demonstrated that its antibodies are potent in neutralizing the SARS-CoV-2 variant JN.1, the parental strain of the currently most dominantly circulating variants worldwide.
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Test tube, dropper
Immuno-oncology

CM-313 exhibits strong antiproliferative activity against multiple CD38+ tumors

June 3, 2024
CD38 is a cell surface receptor, up-regulated in several types of tumors, and involved in cell activation, proliferation and differentiation.
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Immuno-oncology

Preclinical profile of inter-species cross-reactive GNUV-201 antibody

May 30, 2024
Programmed cell death protein 1 (PD-1) is among the immune checkpoint molecules better explored in immunotherapy for cancer. However, it is necessary to obtain novel therapies where preclinical efficacy and safety data could translate into enhanced predictability of human efficacy, pharmacokinetics and side effects.
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Endocrine/metabolic

Sixpeaks Bio emerges with pipeline of weight loss therapies

May 22, 2024
Sixpeaks Bio AG has emerged from stealth with $30 million in series A financing and a pipeline of therapies for healthy weight loss, including a dual-specific antibody targeting activin type IIA and B receptors for preservation of skeletal muscle mass.
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Antibodies attacking cancer cell
Immuno-oncology

OX40-targeting antibody displays agonistic and antitumor activity in preclinical studies

May 22, 2024
Genmab A/S, in collaboration with Biontech SE, has presented data on a novel OX40 agonist antibody –Hexabody-OX40 (GEN-1055/BNT-315), developed using Genmab’s proprietary Hexabody platform, which promotes the formation of antibody hexamers upon target binding to cell surfaces.
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Cholesterol plaque in artery
Endocrine/metabolic

CSPC Pharmaceutical’s JMT-202 cleared to enter clinic in China for hypertriglyceridemia

May 17, 2024
CSPC Pharmaceutical Group Ltd.’s anti-βKlotho monoclonal antibody drug JMT-202 has received clearance from China’s National Medical Products Administration (NMPA) to enter clinical trials to lower triglyceride levels in patients with hypertriglyceridemia.
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3D illustration of human digestive system
Immuno-oncology

Bolt Biotherapeutics unveils Claudin 18.2-targeting ISAC candidate

May 15, 2024
Bolt Biotherapeutics Inc. has unveiled BDC-4182, a next-generation Boltbody immune-stimulating antibody conjugate (ISAC) clinical candidate targeting Claudin 18.2.
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