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Home » Topics » Drugs » Antibody-drug conjugate

Antibody-drug conjugate
Antibody-drug conjugate RSS Feed RSS

3D illustration of tumor
Immuno-oncology

Sun Pharma Advanced Research files IND for SBO-154 for advanced solid tumors

March 31, 2025
Sun Pharma Advanced Research Co. Ltd. has filed an IND application with the FDA for SBO-154 for the treatment of solid tumors. A global phase I study is planned in advanced solid tumors.
Read More
Art concept for tumor
Immuno-oncology

CSPC Pharmaceutical’s SYS-6040 cleared to enter clinic in China for advanced solid tumors

March 21, 2025
CSPC Pharmaceutical Group Ltd. has obtained clearance from China’s National Medical Products Administration (NMPA) to conduct clinical trials with SYS-6040 for advanced solid tumors.
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Elevation buries claudin 18.2 ADC for cancer, slashes staff by 70%

March 20, 2025
By Karen Carey
Elevation Oncology Inc. has nixed its lead pipeline product, a claudin 18.2 antibody-drug conjugate (ADC) called EO-3021, on disappointing phase I data, sending shares tumbling by 42% and placing its preclinical HER3 ADC to the forefront of development.
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Immuno-oncology

Axcynsis Therapeutics discovers new antibody-drug conjugates

March 20, 2025
Axcynsis Therapeutics Pte Ltd. has described antibody-drug conjugates comprising an antibody or antigen-binding fragment targeting alkaline phosphatase placental type (ALPP) and/or alkaline phosphatase, germ cell type (ALPPL2) covalently linked to a cytotoxic agent through a linker reported to be useful for the treatment of cancer.
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Immuno-oncology

Pinotbio divulges new camptothecin derivatives for cancer

March 20, 2025
Pinotbio Inc. has synthesized camptothecin derivatives and its antibody-drug conjugates reported to be useful for the treatment of cancer.
Read More
Gold dollar sign inside gold cog

Taiho acquiring Araris in $1.14B ADC deal

March 18, 2025
By Nuala Moran
The antibody-drug conjugate (ADC) juggernaut powers on, with Japan’s Taiho Pharmaceutical Co. set to acquire Araris Biotech AG for up to $1.14 billion. Of that, $400 million will be up front, with the remainder tied to milestones with a maximum value of $740 million, around the progress of three ADCs for treating solid and hematological cancers.
Read More
Immuno-oncology

Chinese scientists discover new antibody-drug conjugates

March 18, 2025
Researchers at Concept to Medicine Biotech Co. Ltd., Lepu Biopharma Co. Ltd. and Shanghai Miracogen Inc. have described antibody-drug conjugates consisting of trophoblast glycoprotein (TPBG, 5T4)-targeting antibodies covalently linked to cytotoxic drugs through linkers reported to be useful for the treatment of cancer.
Read More
Rendering of Alteogen’s ALT-B4

Alteogen in $1.35B Medimmune deal; Astrazeneca bids $1B for Esobiotec

March 18, 2025
By Marian (YoonJee) Chu
Alteogen Inc. signed its first billion-dollar partnership this year for ALT-B4 technology through two separate contracts with Astrazeneca plc’s U.K.- and U.S.-based Medimmune subsidiaries worth up to $1.35 billion combined.
Read More
Gold dollar sign inside gold cog

Taiho acquiring Araris in $1.14B ADC deal

March 17, 2025
By Nuala Moran
The antibody-drug conjugate (ADC) juggernaut powers on, with Japan’s Taiho Pharmaceutical Co. set to acquire Araris Biotech AG for up to $1.14 billion. Of that, $400 million will be up front, with the remainder tied to milestones with a maximum value of $740 million, around the progress of three ADCs for treating solid and hematological cancers.
Read More
Rendering of Alteogen’s ALT-B4

Alteogen in $1.35B Medimmune deal; Astrazeneca bids $1B for Esobiotec

March 17, 2025
By Marian (YoonJee) Chu
Alteogen Inc. signed its first billion-dollar partnership this year for ALT-B4 technology through two separate contracts with Astrazeneca plc’s U.K.- and U.S.-based Medimmune subsidiaries worth up to $1.35 billion combined.
Read More
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