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BioWorld - Monday, December 29, 2025
Home » Topics » Drugs » Antibody-drug conjugate

Antibody-drug conjugate
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Sino to acquire Lanova and pipeline for up to $950M

July 22, 2025
By Marian (YoonJee) Chu
No Comments
Sino Biopharmaceutical Ltd. agreed to fully acquire Lanova Medicines Ltd. by buying an additional 95.09% stake in Lanova at a valuation of up to $950.92 million. Considering Lanova’s estimated cash and deposit of $450 million, Hong Kong-headquartered Sino agreed to pay $500.9 million to Lanova on the date of the transaction, set to close within 30 days of all conditions being satisfied, or July 31, 2025.
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HKEX exterior

34 mainland China biotechs file for Hong Kong IPO in H1 2025

July 22, 2025
By Marian (YoonJee) Chu
No Comments
Thirty-six biotechnology, pharmaceutical and medical device companies sought a capital raise on the Hong Kong Stock Exchange in the first half (H1) of 2025, a review by BioWorld found. Of those, 34 companies were from mainland China.
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Opportunity compass with Chinese flag

For big pharma, China is a shopper’s dream

July 22, 2025
By Tamra Sami
No Comments
Big pharma is increasingly shopping in China to fill its pipelines as it faces looming patent cliffs on major blockbusters coupled with growing pricing pressures on drugs. China’s out-licensing deals grew to represent 32% of global deals in the first half of 2025, according to a Jefferies report on China dealmaking.
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Opportunity compass with Chinese flag

For big pharma, China is a shopper’s dream

July 21, 2025
By Tamra Sami
No Comments
Big pharma is increasingly shopping in China to fill its pipelines as it faces looming patent cliffs on major blockbusters coupled with growing pricing pressures on drugs. China’s out-licensing deals grew to represent 32% of global deals in the first half of 2025, according to a Jefferies report on China dealmaking.
Read More
HKEX exterior

34 mainland China biotechs file for Hong Kong IPO in H1 2025

July 18, 2025
By Marian (YoonJee) Chu
No Comments
Thirty-six biotechnology, pharmaceutical and medical device companies sought a capital raise on the Hong Kong Stock Exchange in the first half (H1) of 2025, a review by BioWorld found. Of those, 34 companies were from mainland China.
Read More
HKEX exterior

34 mainland China biotechs file for Hong Kong IPO in H1 2025

July 17, 2025
By Marian (YoonJee) Chu
No Comments
Thirty-six biotechnology, pharmaceutical and medical device companies sought a capital raise on the Hong Kong Stock Exchange in the first half (H1) of 2025, a review by BioWorld found. Of those, 34 companies were from mainland China.
Read More
Multiple myeloma and antibodies

Blenrep misstep? ODAC cites tox, GSK dosing neglect in MM

July 17, 2025
By Randy Osborne
No Comments
The rough ride presaged by briefing documents came to pass for GSK plc with the drug first approved by the U.S. FDA as Blenrep (belantamab mafodotin, bel-maf), as the agency’s Oncologic Drugs Advisory Committee (ODAC) appraised the possibility that the antibody-drug conjugate could return to market for relapsed/refractory multiple myeloma (r/r MM).
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Sino to acquire Lanova and pipeline for up to $950M

July 16, 2025
By Marian (YoonJee) Chu
No Comments
Sino Biopharmaceutical Ltd. agreed to fully acquire Lanova Medicines Ltd. by buying an additional 95.09% stake in Lanova at a valuation of up to $950.92 million. Considering Lanova’s estimated cash and deposit of $450 million, Hong Kong-headquartered Sino agreed to pay $500.9 million to Lanova on the date of the transaction, set to close within 30 days of all conditions being satisfied, or July 31, 2025.
Read More
Antibodies attacking cancer cell
Cancer

DS-3939a ADC for treating TA-MUC1-expressing tumors

July 16, 2025
No Comments
Antibody-drug conjugates (ADCs) are therapeutics that combine an antibody with a cytotoxic payload via a chemical linker to specifically target certain cells. Tumor-associated mucin-1 (TA-MUC1) is a glycosylated form of the MUC1 protein that is expressed in several cancer cells, thus being an interesting target for ADC development.
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More Chinese ADCs enter the clinic as biotech race heats up

July 15, 2025
By Tamra Sami
No Comments
China has proved to be a fertile ground for innovation as evidenced by some big deals in the antibody-drug conjugate (ADC) space, and the number of candidates entering clinical trials in China or being advanced in the U.S. by Chinese companies.
Read More
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