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BioWorld - Tuesday, March 17, 2026
Home » Topics » Drugs » Bispecific antibody

Bispecific antibody
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Lee Byoung-chul, CEO, Kanaph

Kanaph’s $27M IPO to aid multi-modality cancer, immune portfolio

March 17, 2026
By Marian (YoonJee) Chu
No Comments
Multi-modality platform company Kanaph Therapeutics Inc. raised ₩40 billion (US$26.7 million) through its Kosdaq stock sale March 16, becoming the first Korean biotech to go public this year. The Seoul-based company’s shares (KOSDAQ:0082N0) climbed to ₩70,000 in intraday trading before closing at ₩50,600 – 153% higher than the offering price.
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Ha Gyong sik giving a presentation

Kanaph, Imbiologics to kick off 2026 Korea biotech, med-tech IPOs

March 17, 2026
By Marian (YoonJee) Chu
No Comments
Two biotech and three med-tech companies are slated for Kosdaq debuts this month, signaling a potential rebound for Korea financings in 2026. Kanaph Therapeutics Inc. will open with a ₩40 billion (US$26.99 million) raise and Imbiologics Corp. will debut with ₩52 billion. Additionally, Mezoo Co. Ltd., Cosmo Robotics Co. Ltd. and Recensmedical Inc. will launch IPOs.
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Fibroblast illustration
Cancer

Mestag raises $40M to take fibroblast program into phase I cancer trial

March 17, 2026
By Nuala Moran
No Comments
Mestag Therapeutics Ltd. has raised a $40 million round from existing investors as it completes final preparations for its lead program MST-0312 to enter clinical development in mid-2026. MST-0312 is a bispecific antibody aimed at the lymphotoxin-β receptor (LTBR), which is essential for the development of lymphoid tissues.
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Lee Byoung-chul, CEO, Kanaph

Kanaph’s $27M IPO to aid multi-modality cancer, immune portfolio

March 16, 2026
By Marian (YoonJee) Chu
No Comments
Multi-modality platform company Kanaph Therapeutics Inc. raised ₩40 billion (US$26.7 million) through its Kosdaq stock sale March 16, becoming the first Korean biotech to go public this year. The Seoul-based company’s shares (KOSDAQ:0082N0) climbed to ₩70,000 in intraday trading before closing at ₩50,600 – 153% higher than the offering price.
Read More
3D illustration of T cells fighting cancer
Immuno-oncology

JNJ-79032421, a membrane-restricted MSLN-targeting T-cell-engaging bispecific antibody

March 16, 2026
No Comments
In a recent publication, researchers from Johnson & Johnson presented a bispecific antibody – JNJ-79032421 – targeting CD3 on T cells and the membrane-restricted, non-shed region of full-length mesothelin (MSLN) on cancer cells.
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Ha Gyong sik giving a presentation

Kanaph, Imbiologics to kick off 2026 Korea biotech, med-tech IPOs

March 13, 2026
By Marian (YoonJee) Chu
No Comments
Two biotech and three med-tech companies are slated for Kosdaq debuts this month, signaling a potential rebound for Korea financings in 2026. Kanaph Therapeutics Inc. will open with a ₩40 billion (US$26.99 million) raise and Imbiologics Corp. will debut with ₩52 billion. Additionally, Mezoo Co. Ltd., Cosmo Robotics Co. Ltd. and Recensmedical Inc. will launch IPOs.
Read More
Skin irritation on hands
Immune

HX-16108 holds promise for treating inflammatory skin diseases

March 11, 2026
No Comments
Atopic dermatitis (AD) is an inflammatory skin disease accompanied by pruritus, for which IL-13 and IL-31 are clinically validated targets. Earendil Labs Inc. has developed a bispecific antibody targeting both IL-13 and IL-31, HX-16108, with an extended half-life.
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Green and red bispecific antibodies
Dermatologic

China’s NMPA clears HBM-7575 to enter clinic in atopic dermatitis

March 9, 2026
No Comments
Harbour Biomed Ltd. and Sichuan Kelun-Biotech Biopharmaceutical Co. Ltd. have announced IND approval by China’s National Medical Products Administration (NMPA) for HBM-7575 (SKB-575) for the treatment of atopic dermatitis.
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3d rendering of bispecific antibodies
Immuno-oncology

CD19xγδ bispecific antibody selectively activates Vγ9Vδ2 T cells for the treatment of B-ALL

March 6, 2026
No Comments
B-cell acute lymphoblastic leukemia (B-ALL), characterized by the clonal expansion of immature lymphoblastic cells, is traditionally treated with lengthy chemotherapy followed by allogeneic stem cell transplantation (aSCT) for high-risk patients. However, patients with relapsed or refractory B-ALL still present a dismal prognosis.
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Cancer tumor in breast illustration

Systimmune’s iza-bren hits phase III breast cancer goals in China

March 3, 2026
By Marian (YoonJee) Chu
No Comments
In a boon for licensee Bristol Myers Squibb Co., Systimmune Inc.’s next-generation cancer drug, izalontamab brengitecan (iza-bren), hit both progression-free survival and overall survival endpoints in a phase III trial of Chinese patients with advanced triple-negative breast cancer.
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