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Home » Topics » Drugs » Cell therapy

Cell therapy
Cell therapy RSS Feed RSS

Human NK cell
Immuno-oncology

EMA grants IMPD approval for Emercell to study allogeneic NK cell therapy for DLBCL

April 25, 2025
Onward Therapeutics SA’s subsidiary Emercell SAS has received investigational medicinal product dossier (IMPD) approval from the EMA to initiate a phase I trial of OT-C001, an allogeneic natural killer (NK) cell therapy, in combination with an anti-CD20 monoclonal antibody, rituximab.
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Art concept for tumor
Cancer

NKG2D-CAR-iMSCs show enhanced targeting of tumors expressing NKG2D ligand in vitro and in vivo

April 24, 2025
Mesenchymal stem cells (MSCs) have long been recognized for their potential in cancer therapy. However, the effectiveness of MSCs in cancer treatment has been hampered by their limited tumor-homing ability and the heterogeneity of tissue-derived MSCs. To address these challenges, researchers have focused on induced pluripotent stem cell (iPSC)-derived MSCs, which offer improved homogeneity and expansion potential.
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Concept art for stem cell implantation

Stem cell therapies show safety in clinical trials in Parkinson's

April 16, 2025
By Mar de Miguel
Stem cell implantation is a step closer to becoming the next strategy against Parkinson's disease. Two clinical trials, one in phase I and the other in phase I/II, have demonstrated their safety and potential to restore dopamine production in the brains of patients with this currently incurable neurodegenerative condition. The number of participants in the study is still small, and further research is needed to demonstrate the clinical benefits of these cell therapies.
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Induced pluripotent stem cells
Neurology/psychiatric

Xellsmart announces US IND clearances for iPSC-derived cell therapies for Parkinson’s disease and ALS

April 16, 2025
Xellsmart Biopharmaceutical (Suzhou) Co. Ltd. has announced IND clearances by the FDA for its XS-411 and XS-228 cell therapies, for Parkinson’s disease and amyotrophic lateral sclerosis (ALS), respectively.
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Sumitomo Pharma offloads two more subsidiaries

April 8, 2025
By Marian (YoonJee) Chu
Sumitomo Pharma Co. Ltd. announced that it will sell off two more of its subsidiaries, Sumitomo Pharma (China) Co. Ltd. and Sumitomo Pharma Asia Pacific Pte. Ltd. (and their subsidiaries), to Marubeni Global Pharma Corp. April 1, as the Japanese pharma continues restructuring efforts from last year.
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3D rendering of CAR T therapy in cell

Cartesian math works out nicely in phase IIb MG trial

April 8, 2025
By Randy Osborne
Cartesian Therapeutics Inc. followed up December’s phase IIb data with more good news regarding Descartes-08, offering 12-month efficacy and safety results that whetted Wall Street’s appetite for the phase III Aurora effort ahead. Milos Miljkovic, chief medical officer, told BioWorld that minimum symptom expression – among the areas where Descartes-08 shone, providing relief for “months and months after the last dose of treatment” – is especially important to patients.
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Neurona closes a $102M financing

April 4, 2025
By Lee Landenberger
Neurona Therapeutics Inc. has completed an upsized, oversubscribed $102 million financing round, the third company to do so in a month that’s only four days old. The privately held company’s lead asset is NRTX-1001, a regenerative cell therapy derived from human pluripotent stem cells. 
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Sumitomo Pharma offloads two more subsidiaries

April 3, 2025
By Marian (YoonJee) Chu
Sumitomo Pharma Co. Ltd. announced that it will sell off two more of its subsidiaries, Sumitomo Pharma (China) Co. Ltd. and Sumitomo Pharma Asia Pacific Pte. Ltd. (and their subsidiaries), to Marubeni Global Pharma Corp. April 1, as the Japanese pharma continues restructuring efforts from last year.
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BIO survey points to ‘damaging impacts’ of Trump tariffs

March 27, 2025
By Nuala Moran
A survey of members of the Bioindustry Innovation Organization (BIO) has exposed what is at stake for the sector, on both sides of the Atlantic, if proposed tariffs are imposed on pharmaceutical imports to the U.S. "A staggering 94% of biotech firms anticipate surging manufacturing costs if tariffs are placed on imports from the EU,” according to BIO.
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3D illustration of mesenchymal stem cells

Nature Cell wins FDA breakthrough designation of Jointstem

March 25, 2025
By Marian (YoonJee) Chu
Nature Cell Co. Ltd. won U.S. FDA breakthrough therapy designation of its autologous adipose-derived mesenchymal stem cell therapy, Jointstem, March 20, becoming the first Korean company to earn the label in the field of cell therapy.
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