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Home » Topics » Drugs » Cell therapy

Cell therapy
Cell therapy RSS Feed RSS

Antibody-drug conjugate

Ligachem gets rights to Daan’s antibody for solid tumor ADCs

Feb. 13, 2025
By Marian (YoonJee) Chu
Ligachem Biosciences Inc. landed another exclusive licensing deal to develop and commercialize antibody-drug conjugates (ADCs), this time with T-cell receptor therapy specialist Daan Biotherapeutics Inc. for a cancer-targeting antibody.
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Stem cells

‘Exciting data’: S.Biomedics preps US IND of PD cell therapy

Feb. 4, 2025
By Marian (YoonJee) Chu
To realize the promise of cell therapy for neurodegenerative disorders, S.Biomedics Co. Ltd. is looking to expand clinical trials of TED-A9, its stem cell therapy for Parkinson’s disease (PD), to the U.S., having reaped positive results from a domestic phase I/IIa trial in November 2024.
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Cargo stops firi-cel phase II on safety, durability; stock sinks

Jan. 30, 2025
By Karen Carey
In a devastating blow to the company and large B-cell lymphoma patients relapsed or refractory to CD19 CAR T-cell therapy, Cargo Therapeutics Inc. terminated the phase II study of its lead CD22 cell therapy, firicabtagene autoleucel (firi-cel), and is cutting its workforce by 50% and evaluating strategic options, following disappointing data on durability of response and serious safety events, some of which were fatal.
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Immuno-oncology

Swarm Oncology launches with focus on T-cell therapies for solid cancers

Jan. 27, 2025
Swarm Oncology Ltd. has emerged from stealth with a focus on advancing novel T-cell therapies to achieve long-term remission in patients with advanced solid cancers.
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Stem cells

‘Exciting data’: S.Biomedics preps US IND of PD cell therapy

Jan. 23, 2025
By Marian (YoonJee) Chu
To realize the promise of cell therapy for neurodegenerative disorders, S.Biomedics Co. Ltd. is looking to expand clinical trials of TED-A9, its stem cell therapy for Parkinson’s disease (PD), to the U.S., having reaped positive results from a domestic phase I/IIa trial in November 2024.
Read More
Omniabio building

Medipost grows US, Canada base; plans US phase III of Cartistem

Jan. 21, 2025
By Marian (YoonJee) Chu
As more Asia biotechs turn to regenerative medicine to address disorders without a cure, Medipost Inc. is continuing global expansion with Cartistem, its allogeneic human umbilical cord blood-derived mesenchymal stem cell product that gained clearance in South Korea in 2012 to treat knee osteoarthritis.
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Illustration of Epstein-Barr virus particles

Atara sinks on Ebvallo CRL, seeks strategic alternatives

Jan. 16, 2025
By Karen Carey
Atara Biotherapeutics Inc. received a complete response letter (CRL) from the U.S. FDA for its lead product, Ebvallo (tabelecleucel), a breakthrough therapy for Epstein-Barr virus positive post-transplant lymphoproliferative disease that is already approved in the EU, the U.K. and Switzerland.
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Colorized transmission electron micrograph of avian influenza A H5N1 virus particles
Infection

TC Biopharm looks to begin proof-of-concept preclinical studies for TCB-008 to treat H5N1

Jan. 16, 2025
TC Biopharm (Holdings) plc intends to begin proof-of-concept preclinical studies for its lead therapeutic TCB-008, to treat H5N1, or bird flu. TCB-008 is an allogeneic, unmodified cell therapy comprised of activated and expanded γδ T cells.
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Omniabio building

Medipost grows US, Canada base; plans US phase III of Cartistem

Jan. 15, 2025
By Marian (YoonJee) Chu
As more Asia biotechs turn to regenerative medicine to address disorders without a cure, Medipost Inc. is continuing global expansion with Cartistem, its allogeneic human umbilical cord blood-derived mesenchymal stem cell product that gained clearance in South Korea in 2012 to treat knee osteoarthritis.
Read More

JPM: CBER’s Marks ‘reassured’ as FDA to refine warnings on CAR Ts

Jan. 15, 2025
By Nuala Moran
The U.S. FDA is to temper the alert it put out in November 2023 pointing to a potential risk of CAR T therapies causing de novo malignancies. “There was this issue of possible safety concerns with T-cell lymphomas, with these CAR T cells. I think this year, we are feeling reassured in this regard,” Peter Marks, director of the FDA’s Center for Biologics Evaluation and Research (CBER), told the Alliance for Regenerative Medicine briefing at the J. P. Morgan Healthcare Conference on Jan. 13.
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