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BioWorld - Wednesday, April 22, 2026
Home » Topics » Drugs » Monoclonal antibody

Monoclonal antibody
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Global handshake silhouette

Biogen amasses full felzartamab rights with $850M TJ deal

April 21, 2026
By Marian (YoonJee) Chu
No Comments
Biogen Inc. has consolidated full global rights to felzartamab through an $850 million deal with TJ Biopharma Co. Ltd. April 20, closing the chapter on a complex 10-year license saga.
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3D illustration of platelets in the boodstream
Hematologic

Alethio unveils ATX-011 for essential thrombocythemia

April 16, 2026
No Comments
Alethio Therapeutics Inc. has unveiled ATX-011, a mutation-agnostic antibody for essential thrombocythemia. ATX-011 is a potential first-in-class monoclonal antibody based on a new target identified on mutant stem cells that drive myeloproliferative neoplasm disease progression.
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Ulcerative colitis

Spyre’s SPY-001 induces better outcomes in ulcerative colitis

April 13, 2026
By Brian Orelli
No Comments
Spyre Therapeutics Inc. is off to a good start in its goal to create the best combination therapy for inflammatory bowel disease, a group of chronic, relapsing autoimmune conditions of the digestive tract that encompasses Crohn’s disease and ulcerative colitis. The Waltham, Mass.-based company estimates the market for IBD is currently at approximately $25 billion but will jump to around $40 billion in 2030.
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Photo of measles rash on skin
Infection

Invivyd unveils measles monoclonal antibody candidate VMS-063

April 10, 2026
No Comments
Invivyd Inc. has announced the discovery and advancement of VMS-063, a novel monoclonal antibody candidate for the treatment and prevention of measles.
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Tape measure, apple on scale
Endocrine/metabolic

Ibio’s IBIO-600 cleared to enter clinic in Australia for obesity

April 9, 2026
No Comments
Ibio Inc. has received clinical trial notification (CTN) acknowledgement from Australia’s Therapeutic Goods Administration (TGA), as well as Human Research Ethics Committee approval, for IBIO-600, enabling the initiation of a first-in-human trial in Australia.
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PET scans showing before and after treatment with VIPOR
ICKSH 2026

Five-drug VIPOR regimen shows promise in aggressive blood cancer

April 7, 2026
By Marian (YoonJee) Chu
No Comments
Deep molecular advances are enabling precision medicine for the field of hematology, Wyndham Wilson said during a plenary session at the 2026 Korean Society of Hematology International Conference March 26.
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Illustration of monoclonal antibody hovering between doctor's hands
Infection

Longhorn reports long-acting peptidoglycan-targeted mAb for sepsis

April 2, 2026
No Comments
At the World Vaccine Congress this week, Longhorn Vaccines & Diagnostics LLC presented the preclinical characterization of LHNVD-501, a half-life-extended, humanized IgG monoclonal antibody (mAb) targeting peptidoglycan (PGN). PGN is a conserved structural component shared across bacterial species and an upstream driver of sepsis, as well as metabolic disease, autoimmune disorders and neurodegeneration.
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PET scans showing before and after treatment with VIPOR
ICKSH 2026

Five-drug VIPOR regimen shows promise in aggressive blood cancer

April 1, 2026
By Marian (YoonJee) Chu
No Comments
Deep molecular advances are enabling precision medicine for the field of hematology, Wyndham Wilson said during a plenary session at the 2026 Korean Society of Hematology International Conference March 26.
Read More
Monoclonal antibody illustration

Simcere’s rademikibart meets phase III endpoints in atopic dermatitis

March 31, 2026
By Tamra Sami
No Comments
Simcere Pharmaceutical Group Ltd.’s monoclonal antibody, rademikibart (CBP-201), met the primary endpoint in a Chinese phase III study in adults and adolescents with moderate to severe atopic dermatitis.
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Immuno-oncology

Tyligand Bioscience divulges new dual-drug antibody-drug conjugates

March 31, 2026
Tyligand Bioscience Ltd. has reported new dual-drug antibody-drug conjugates comprising monoclonal antibodies covalently linked to stimulator of interferon genes protein (STING; TMEM173) agonist and a cytotoxic drug.
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