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BioWorld - Friday, December 26, 2025
Home » Topics » Drugs » Protein

Protein
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Breast cancer illustration
Immuno-oncology

New granzyme B-based immunotoxin targeting breast cancer, including TNBC

Jan. 17, 2025
Researchers have developed an innovative immunotoxin (a fusion protein called GrB-Fc-KS49) designed to target epithelial membrane protein-2 (EMP2), a biomarker overexpressed in more than 75% of breast cancer cases, including triple-negative breast cancer (TNBC).
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Immune

Vera Therapeutics licenses rights to BAFF/APRIL inhibitor from Stanford University

Jan. 14, 2025
Vera Therapeutics Inc. entered a license agreement with Stanford University.
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Gilead, Leo Pharma join in $1.7B deal for STAT6 program

Jan. 13, 2025
By Nuala Moran
Gilead Sciences Inc. is moving further into inflammatory diseases in a potential $1.7 billion deal with Leo Pharma A/S around a preclinical oral signal transduction and activator of transcription 6 (STAT6) program that the Danish dermatology specialist has been working on since 2018.
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3D illustration of cancer in crosshairs
Immuno-oncology

Fapon Biopharma presents immunocytokine for anti-PD-1 refractory cancers

Jan. 2, 2025
Guangdong Fapon Biopharma Inc. is developing its immunocytokine FP-008 for cancers that are refractory to anti-PD-1 therapies.
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Flagship’s Generate Bio scores investment from Samsung fund

Dec. 24, 2024
By Marian (YoonJee) Chu
A year after Generate Biomedicines Inc. pulled off its $273 million series C financing round, the Flagship Pioneering-spawned and AI-powered protein therapeutics firm drew investment of an undisclosed amount from the Samsung Life Science Fund Dec. 18.
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Flagship’s Generate Bio scores investment from Samsung fund

Dec. 20, 2024
By Marian (YoonJee) Chu
A year after Generate Biomedicines Inc. pulled off its $273 million series C financing round, the Flagship Pioneering-spawned and AI-powered protein therapeutics firm drew investment of an undisclosed amount from the Samsung Life Science Fund Dec. 18.
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Blood pressure cuff

Keros stock wilts as it halts two dosing arms in hypertension study

Dec. 12, 2024
By Lee Landenberger
After Keros Therapeutics Inc.’s voluntary halt of dosing in two arms of its phase II study in pulmonary arterial hypertension, the company’s stock crumpled after a year of muscular performance and its recent and massive deal with Takeda Pharmaceutical Co. Ltd.
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Art concept for hematologic cancer

Takeda bolsters oncology pipeline via $1.3B deal for Keros’ elritercept

Dec. 10, 2024
By Tamra Sami
Takeda Pharmaceutical Co. Ltd. is licensing Keros Therapeutics Inc.’s activin inhibitor elritercept in a global development and commercialization deal worth up to $1.3 billion that excludes mainland China, Hong Kong and Macau.
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Art concept for hematologic cancer

Takeda bolsters oncology pipeline via $1.3B deal for Keros’ elritercept

Dec. 4, 2024
By Tamra Sami
Takeda Pharmaceutical Co. Ltd. is licensing Keros Therapeutics Inc.’s activin inhibitor elritercept in a global development and commercialization deal worth up to $1.3 billion that excludes mainland China, Hong Kong and Macau.
Read More
Immuno-oncology

Proximity-activated antibody-cytokine fusion protein reinvigorates tumor-specific PD-1-expressing T cells

Nov. 29, 2024
Researchers from Anaveon AG and affiliated organizations presented the discovery and preclinical characterization of ANV-700, a novel proximity-activated cytokine (PAC) compound designed to selectively deliver IL-21 to PD-1-expressing cells for the treatment of cancer.
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