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BioWorld - Saturday, April 18, 2026
Home » Topics » Asia-Pacific » Australia

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Chimeric surges on first phase I data for CLTX CAR T in glioblastoma

Oct. 24, 2023
By Tamra Sami
Chimeric Therapeutics Ltd.‘s chlorotoxin (CLTX) CAR T therapy, CHM-1101, which is derived from scorpion toxin, saw a disease control rate of 55%, exceeding the historical disease control rates of 20% to 37% in heavily pre-treated patients with glioblastoma.
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Knee pain illustration

Holy grail? Paradigm’s injectable Zilosul shows disease-modifying attributes in osteoarthritis

Oct. 24, 2023
By Tamra Sami
A six-week treatment regimen of Paradigm Biopharmaceuticals Ltd.’s Zilosul (injectable pentosan polysulfate/iPPS) resulted in improvement of both the symptoms of osteoarthritis and preserved or regenerated joint tissues in the knee, according to phase II trial results.
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ESMO 2023: Immutep’s LAG-3 immunotherapy shows 35.5 months overall survival in NSCLC

Oct. 24, 2023
By Tamra Sami
Immutep Ltd.’s lead candidate, eftilagimod (IMP-321, efti), a lymphocyte activation gene-3 (LAG-3) fusion protein and major histocompatibility complex class II agonist, delivered an overall survival benefit of 35.5 months in the TACTI-002 trial that combined efti with Merck & Co. Inc.’s Keytruda (pembrolizumab) as first-line treatment of non-small-cell lung cancer (NSCLC) at two years follow-up.
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Illustration comparing healthy vs. Huntington's disease neuron and brain
Neurology/Psychiatric

Skyhawk’s RNA splicing modifier for Huntington’s disease cleared for Australian trial

Oct. 24, 2023
Skyhawk Therapeutics Inc. has obtained Australian human research ethic committee (HREC) approval to conduct a phase I trial of SKY-0515 for Huntington’s disease.
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Chimeric surges on first phase I data for CLTX CAR T in glioblastoma

Oct. 23, 2023
By Tamra Sami
Chimeric Therapeutics Ltd.‘s chlorotoxin (CLTX) CAR T therapy, CHM-1101, which is derived from scorpion toxin, saw a disease control rate of 55%, exceeding the historical disease control rates of 20% to 37% in heavily pre-treated patients with glioblastoma.
Read More
Microchip robotic manufacturing concept

Microsurgery robotics firm MMI expands to APAC through two local partners

Oct. 20, 2023
By Marian (YoonJee) Chu
Medical Microinstruments Inc. (MMI) is expanding its Symani surgical system into the Asia Pacific – a region with “clear demand for the technology” – through two local partners, Device Technologies Australia Pty Ltd. and Seoul-based TRM Korea Corp.
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Pancreas
Endocrine/Metabolic

Sab's fully human anti-thymocyte immunoglobulin cleared to enter clinic in Australia for type 1 diabetes

Oct. 20, 2023
Sab Biotherapeutics Inc. has obtained human research ethics committee (HREC) approval in Australia to commence a first-in-human phase I trial investigating SAB-142 for type 1 diabetes.
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Knee pain illustration

Holy grail? Paradigm’s injectable Zilosul shows disease-modifying attributes in osteoarthritis

Oct. 19, 2023
By Tamra Sami
A six-week treatment regimen of Paradigm Biopharmaceuticals Ltd.’s Zilosul (injectable pentosan polysulfate/iPPS) resulted in improvement of both the symptoms of osteoarthritis and preserved or regenerated joint tissues in the knee, according to phase II trial results.
Read More
Gastric cancer
Newco news

Immunotherapy company Arbele banking on cadherin-17 as target for gastrointestinal cancers

Oct. 10, 2023
By Tamra Sami
Arbele Ltd. founder and CEO John Luk identified and patented cadherin-17 as a therapeutic cancer target, and the company was founded to develop immunotherapies for gastrointestinal cancers, which are prevalent in Asia Pacific.
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dental splint sleep apnea therapy
Patents

Australian dentists develop dental splint for treating sleep apnea and snoring

Oct. 10, 2023
Dentists at Melbourne, Australia-based 3DSG Pty Ltd. are seeking patent protection for a plug and socket set for use in a mandibular advancement splint set for treating snoring or sleep apnea.
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