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BioWorld - Monday, April 20, 2026
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Truffle hunting: Truffle Capital closes 5th Biomedtech fund at $279M

Dec. 18, 2019
By Cormac Sheridan
DUBLIN – Truffle Capital closed off its fifth Biomedtech fund with a €250 million (US$279 million) raise, which it will deploy in about a dozen companies located mainly in France. The fund took a little longer to close than originally planned but it is significantly larger than it had originally intended. “Our initial objective was €200 million,” Truffle Capital CEO and co-founder Philippe Pouletty told BioWorld.
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French-based data science team develops AI tool for predicting cancer drug approval following phase I trials

Dec. 16, 2019
By Bernard Banga
PARIS – A team of medical researchers and engineers from the Gustave Roussy Institute, in Villejuif, France, and Paris-Sud University recently developed an artificial intelligence system called Resolved2, designed to assess prospective cancer drugs. As Loïc Verlingue, lead cancer specialist on the data science team at the Gustave Roussy Institute, explained to BioWorld MedTech, “this AI is intended to predict efficiently whether a cancer treatment molecule will achieve authorization or not within six years of pharmacological data and phase I clinical trials.”
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Two positive CHMP opinions in December take 2019 tally to 41

Dec. 13, 2019
By Cormac Sheridan
DUBLIN – The European Medicines Agency’s Committee for Medicinal Products for Human Use closed out its year’s work with positive opinions on two applications, Novartis AG’s Beovu (brolucizumab) in wet age-related macular degeneration and Merck & Co. Inc.’s Recarbrio for treating gram negative infections in adults.
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EMA takes pharmacovigilance to the next level: ‘Nearly’ real-time decision-making

Dec. 13, 2019
By Nuala Moran
LONDON – Over the next decade pharmacovigilance will move on from a sole focus on adverse drug reactions (ADRs) to encompass monitoring of the in-market efficacy of medicines, according to Guido Rasi, executive director of EMA.
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Red blood cells

Enzyre, Takeda team up to develop home diagnostic device for hemophiliacs

Dec. 12, 2019
By Nuala Moran
LONDON – Dutch startup Enzyre BV is teaming up with Takeda Pharmaceutical Co. Ltd. to complete development of a home diagnostic device that aims to make it as easy for hemophiliacs to self-test their coagulation status as it is for diabetics to monitor their blood sugar levels.
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Scientists create artificial neurons capable of mimicking biological counterparts

Dec. 11, 2019
By Nuala Moran
LONDON – Scientists in the U.K. are claiming a world first, after successfully reproducing the electrophysiology of biological neurons in silicon chips. It is said that artificial neurons respond to non-linear physiological feedback in real time, in exactly the same way as their biological counterparts.
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Neural network

Scientists create artificial neurons capable of mimicking biological counterparts

Dec. 11, 2019
By Nuala Moran
LONDON – Scientists in the U.K. are claiming a world first, after successfully reproducing the electrophysiology of biological neurons in silicon chips. It is said that artificial neurons respond to non-linear physiological feedback in real time, in exactly the same way as their biological counterparts. Crucially, in terms of their use in medical implants, the analogue chips have a power consumption 109 times lower than equivalent digital microprocessors, which other attempts to make synthetic neurons have used.
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Grapheal developing intelligent patch to remotely monitor healing of chronic wounds

Dec. 11, 2019
By Bernard Banga
PARIS – Grapheal SAS, of Grenoble, France, is developing a new generation of dressings integrating an embedded electronic biosensor. The Grapheal device consists of monolayer graphene on a polymer layer 0.3 nanometers thick. “This noninvasive embedded device collects data from the wound. The wireless e-health wound monitoring system, or smart patch, remotely reports the status of chronic wounds to the care team,” Vincent Bouchiat, co-founder and CEO at Grapheal, told BioWorld MedTech.
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Advanced Oncotherapy readies first linear proton beam accelerator system for debut

Dec. 9, 2019
By Nuala Moran
LONDON – Advanced Oncotherapy plc is starting verification and validation of the world’s first linear proton beam accelerator system, which is assembled and ready for testing at the Daresbury particle physics laboratory in Cheshire, U.K.
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Person holding knee, joint pain

Celltrion’s Remsima SC wins marketing approval in EU

Dec. 3, 2019
By Jihyun Kim
HONG KONG – Celltrion Healthcare Co. Ltd., a South Korean biopharmaceutical corporation, won European Union (EU) marketing approval for Remsima SC for the treatment of rheumatoid arthritis (RA), as a subcutaneous version of Celltrion’s infliximab biosimilar, CT-P13.
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