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BioWorld - Thursday, July 9, 2026
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Concept art for irregular heart rhythms/arrhythmias caused by mutations in genes.

Growth in AI mapping tools for arrhythmia treatment

Oct. 9, 2024
By Shani Alexander
Rhythm AI Ltd recently became the latest company to receive U.S. FDA clearance for its artificial intelligenc-based software for optimizing Atrial Fibrillation procedures.
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Illustration of 2024 Nobel Prize in Physics winners John Hopfield and Geoffrey Hinton
Drug design, drug delivery & technologies

2024 Physics Nobel goes for foundations of AI

Oct. 9, 2024
By Anette Breindl
It’s hard to know where to start in describing the biopharma applications of the 2024 Nobel Prize in Physics. It was awarded to John Hopfield and Geoffrey Hinton “for foundational discoveries and inventions that enable machine learning with artificial neural networks.”
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Illustration of 2024 Nobel Prize in Physics winners John Hopfield and Geoffrey Hinton

2024 Physics Nobel goes for foundations of AI

Oct. 8, 2024
By Anette Breindl
It’s hard to know where to start in describing the biopharma applications of the 2024 Nobel Prize in Physics. It was awarded to John Hopfield and Geoffrey Hinton “for foundational discoveries and inventions that enable machine learning with artificial neural networks.”
Read More

BioWorld Insider podcast: Gene and cell therapies will propel innovation

Oct. 8, 2024
By Lee Landenberger
Gene and cell therapies will drive innovation for the next 10 years, Claus Zieler, the chief commercial officer at Astellas Pharma Inc., said in the newest episode of the BioWorld Insider podcast. Developers are on the cusp of breakthroughs because a gene can now be replaced “and that means we can potentially cure a disease rather than intervening in a disease.”
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Brain and DNA

Aviadobio, Astellas ink $2B+ frontotemporal dementia gene therapy deal

Oct. 8, 2024
By Nuala Moran
Aviadobio Ltd. has entered a potential $2.18 billion license and commercialization agreement for its frontotemporal dementia gene therapy, AVB-101, with Astellas Pharma Inc. Astellas is making a $20 million equity investment in London-based Aviadobio and will pay up to $30 million up front in advance of deciding whether or not to exercise the exclusive option to worldwide rights.
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Mestag’s activated fibroblast approach draws Merck in $1.9B deal

Oct. 8, 2024
By Nuala Moran
Mestag Therapeutics Ltd. has sealed a potential $1.9 billion agreement with Merck & Co. Inc., in which it will apply its expertise in activated fibroblasts to identify novel targets for inflammatory diseases. The pharma company has the option to license one or more targets, up to a prespecified number, and will take on all subsequent discovery, development and commercialization work.
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BioWorld Insider podcast: Gene and cell therapies will propel innovation

Oct. 7, 2024
By Lee Landenberger
Gene and cell therapies will drive innovation for the next 10 years, Claus Zieler, the chief commercial officer at Astellas Pharma Inc., said in the newest episode of the BioWorld Insider podcast. Developers are on the cusp of breakthroughs because a gene can now be replaced “and that means we can potentially cure a disease rather than intervening in a disease.”
Read More
Green, blue, gray dollar signs

Sofinnova’s Papiernik: ‘It’s a good period for med tech’

Oct. 7, 2024
By Shani Alexander
The recent uptick in med-tech deals is a sign technologies that are solving unmet clinical needs are finally coming to fruition, Antoine Papiernik, chairman and managing partner at Sofinnova Partners, told BioWorld in an interview.
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Kurma closes €140M fund aimed at breakthrough research in Europe

Oct. 7, 2024
By Nuala Moran
Kurma Partners has announced the first closing of its Biofund IV at €140 million (US$154.5 million) and is pressing ahead to a final close of €250 million this time next year. The fund will make 16 to 20 investments, with half the money due to be invested in novel science that Kurma teases out of academic labs and the remainder in established VC-funded companies. The Paris-based firm is agnostic about which fields or disease areas it invests in and will prospect for breakthrough research anywhere in Europe.
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3D dollar sign

Recordati buys rare disease drug Enjaymo in $825M Sanofi deal

Oct. 4, 2024
By Jennifer Boggs
Recordati SpA is shelling out $825 million up front for global rights to Enjaymo (sutimlimab), the only therapy approved for treating the rare disease cold agglutinin disease. In the deal with Sanofi SA, which won U.S. FDA approval of the antibody drug in 2022, the Italian pharma agreed to pay up to $250 million more should net sales reach certain thresholds.
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