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BioWorld - Sunday, May 18, 2025
Home » Topics » Regulatory » Patents

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Implantable electrode assemblies

Researchers develop visual prosthetic to restore sight

March 21, 2025
By Simon Kerton
Researchers from the Albert Einstein College of Medicine filed for protection of the development of a lateral geniculate nucleus (LGN) visual prosthetic device with implantable electrode arrays that stimulate the LGN and restore vision.
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Endocrine/metabolic

Gasherbrum Bio discovers new GLP-1R agonists

March 21, 2025
Gasherbrum Bio Inc. has described glucagon-like peptide 1 receptor (GLP-1R) agonists reported to be useful for the treatment of type 2 diabetes, dyslipidemia, schizophrenia, hypertension, obesity, stroke, myocardial infarction and gout, among others.
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Infection

Nucleoside prodrugs for viral infections disclosed in Gilead patent

March 21, 2025
Gilead Sciences Inc. has divulged nucleoside prodrugs reported to be useful for the treatment of viral infections.
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Cancer

Eikon Therapeutics describes new WRN inhibitors

March 21, 2025
Eikon Therapeutics Inc. has identified Werner syndrome ATP-dependent helicase (WRN; RECQ3; RECQL2) inhibitors reported to be useful for the treatment of cancer.
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Endocrine/metabolic

Agios Pharmaceuticals divulges new PAH stabilizers for phenylketonuria

March 21, 2025
Agios Pharmaceuticals Inc. has synthesized phenylalanine hydroxylase (PAH) R408W mutant stabilizers reported to be useful for the treatment of phenylketonuria.
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Cancer

Juno Therapeutics patents new DNA-PK inhibitors

March 21, 2025
Juno Therapeutics Inc. has disclosed DNA-dependent protein kinase (DNA-PK) inhibitors reported to be useful for the treatment of cancer.
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WO2025049953-A1, “Conductive microwire-based biochemical sensors for real-time neurological monitoring.”

Neurothread biosignal monitoring could sew up neurological diagnoses

March 20, 2025
By Simon Kerton
Researchers from The Ohio State University have filed for protection of Neurothread, a wire-type neurotransmitter-sensing platform that utilizes the cross-section of commercially available ultrathin microwires as microelectrodes.
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Immuno-oncology

Axcynsis Therapeutics discovers new antibody-drug conjugates

March 20, 2025
Axcynsis Therapeutics Pte Ltd. has described antibody-drug conjugates comprising an antibody or antigen-binding fragment targeting alkaline phosphatase placental type (ALPP) and/or alkaline phosphatase, germ cell type (ALPPL2) covalently linked to a cytotoxic agent through a linker reported to be useful for the treatment of cancer.
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Cancer

New PARG inhibitors disclosed in Forx patent

March 20, 2025
Forx Therapeutics AG has divulged poly(ADP-ribose) glycohydrolase (PARG) inhibitors reported to be useful for the treatment of cancer.
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Infection

Revagenix describes new aminoglycosides to treat bacterial infections

March 20, 2025
Revagenix Inc. has identified aminoglycosides reported to be useful for the treatment of bacterial infections.
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