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BioWorld - Monday, June 15, 2026
Home » Topics » Regulatory » Patents

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Cancer

Beijing Earthwise Technology identifies new CBL-B inhibitors

March 11, 2026
Beijing Earthwise Technology Co. Ltd. has described E3 ubiquitin-protein ligase CBL-B (CBLB) inhibitors reported to be useful for the treatment of cancer.
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Cancer

Synnocare Pharmaceutical discloses DHX9 inhibitors

March 10, 2026
Nanjing Synnocare Pharmaceutical Technology Co. Ltd. and Shanghai Synnocare Biopharmaceuticals Co. Ltd. have patented ATP-dependent RNA helicase A (DHX9) inhibitors with potential for use in the treatment of cancer, autoimmune and viral infections.
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Ocular

Roche identifies new soluble epoxide hydrolase inhibitors

March 10, 2026
F. Hoffmann-La Roche Ltd. and Hoffmann-La Roche Inc. have synthesized pyridone carboxamide-derived compounds acting as soluble epoxide hydrolase inhibitors. They are reported to be useful for the treatment of diabetic retinopathy, neuropathic pain and neurodegenerative diseases.
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Neurology/psychiatric

Shanghai 3D Medicines Laboratory synthesizes Nav1.8 blockers for pain

March 10, 2026
Work at Shanghai 3D Medicines Laboratory Co. Ltd. has led to the discovery of new sodium channel protein type 10 subunit α (SCN10A; Nav1.8) blockers designed for use in the treatment of pain.
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Endocrine/metabolic

GIPR antagonists reported in Pfizer patent

March 10, 2026
Pfizer Inc. has identified 4-{4-[(1-{[4-(propan-2-yl)phenyl]carbamoyl)-D-prolyl)amino]cyclohexyl}benzoic acid derivatives acting as gastric inhibitory polypeptide receptor (GIPR) antagonists. As such, they are described as potentially useful for the treatment of type 2 diabetes and obesity.
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HIV/AIDS

Shionogi patents new agents for HIV-1 infection

March 10, 2026
Shionogi & Co. Ltd. has disclosed heterocyclic derivatives characterized as reverse transcriptase/ribonuclease H (HIV-1) inhibitors for potential use in the treatment of HIV infection.
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Immune

Chinese researchers discover new PDE4B inhibitors

March 9, 2026
Scientists from Fu Wai Hospital of the Chinese Academy of Medical Sciences and Shenzhen Bay Laboratory have divulged cAMP-specific 3',5'-cyclic phosphodiesterase 4B (PDE4B) inhibitors. They are reported to be useful for the treatment of autoimmune diseases, cancer, neurological disorder, diabetes, inflammatory bowel disease, pulmonary fibrosis, psoriasis and arthritis, among others.
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Cancer

Shanghai Deep Potential Technology synthesizes new PLK1 inhibitors

March 9, 2026
Shanghai Deep Potential Technology Co. Ltd. has discovered serine/threonine-protein kinase PLK1 (STPK13) inhibitors reported to be useful for the treatment of cancer.
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Cancer

Shanghai Chempartner describes new ADCs targeting HER2 and TROP2

March 9, 2026
Shanghai Chempartner Co. Ltd. has identified antibody-drug conjugates (ADCs) comprising HER2 (erbB2) or tumor-associated calcium signal transducer 2 (TACSTD2; TROP2) covalently linked to eribulin through a linker reported to be useful for the treatment of cancer.
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Neurology/psychiatric

Jiangxi Kerui Pharma discloses new KCNQ2/3 activators

March 9, 2026
Jiangxi Kerui Pharmaceutical Co. Ltd. has patented potassium voltage-gated channel subfamily KQT member 2/3 (KCNQ2/3) activators. They are reported to be useful for the treatment of anxiety disorders, depression, pain, focal seizures and tonic clonic epilepsy.
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