Chia Tai Tianqing Pharmaceutical Group Co. Ltd. has disclosed RAC-α serine/threonine-protein kinase (AKT1; PKB α) (Glu17Lys mutant) inhibitors reported to be useful for the treatment of leukemia.

Alicorn Pharmaceutical Co. Ltd. has described protein arginine N-methyltransferase 5 (PRMT5) inhibitors reported to be useful for the treatment of cancer.

Meta Pharmaceuticals Inc. and Shenzhen Moyuan Pharmaceuticals Co. Ltd. have divulged lactate dehydrogenase A (LDHA) inhibitors reported to be useful for the treatment of autoimmune disorders.

Liaoning Haisco Pharmaceutical Co. Ltd. has identified crystalline salts of known cholesterol side-chain cleavage enzyme, mitochondrial (CYP11A1) inhibitors reported to be useful for the treatment of cancer.

Farsight Medical Technology (Shanghai) Co. Ltd. has synthesized cyclosporin derivatives acting as peptidyl-prolyl cis-trans isomerase F, mitochondrial (PPIF; cyclophilin D) and/or peptidyl-prolyl cis-trans isomerase A (PPIA; cyclophilin A; CYPA) inhibitors reported to be useful for the treatment of asthma, cancer, multiorgan failure, viral infections, rheumatoid arthritis, renal disorders, neurological disorders and cardiovascular disorders, among others.

Shanghai Fosun Pharmaceutical Industry Development Co. Ltd. has disclosed kinesin-like protein KIF18A inhibitors reported to be useful for the treatment of cancer.

Scientists at Osaka University and Tokyo University of Science have described compounds targeting Claudin-5 (CLDN5) acting as blood-brain barrier (BBB) permeability regulators reported to be useful for the treatment of sepsis, cerebral edema, infections, epilepsy, multiple sclerosis, psychiatric disorders, Alzheimer’s disease and Parkinson’s disease, among others.

Kong’s Pharmaceutical Co. has divulged Ras-related C3 botulinum toxin substrate 1 (RAC1; TC25) inhibitors reported to be useful for the treatment of cancer and neurologic disorders.

Chinese University of Hong Kong has identified peptides acting as serine/arginine-rich protein-specific kinase 1 (SRSF protein kinase 1; SRPK1) inhibitors reported to be useful for the treatment of lung cancer, breast cancer, coronavirus acute respiratory syndrome, hepatitis and herpes viral infections.

Researchers at Meiji Seika Pharma Co. Ltd., National Center of Neurology & Psychiatry and Tokyo University of Pharmacy & Life Sciences have synthesized NAD(+) H\hydrolase SARM1 (SAMD2; MyD88-5) inhibitors reported to be useful for the treatment of neurodegeneration.