Novartis AG has disclosed 3C-like proteinase (3CLpro; Mpro; nsp5) inhibitors reported to be useful for the treatment of SARS-CoV-2 infection.

Shanghai Aryl Pharmtech Co. Ltd. and Zhejiang Hisun Pharmaceutical Co. Ltd. have described pyrimidocyclic derivatives acting as son of sevenless homolog 1 (SOS1) inhibitors reported to be useful for the treatment of cancer, cardiofaciocutaneous and Noonan syndrome.

Theranocure Co. Ltd. has divulged gadolinium complexes targeting β-amyloid protein acting as magnetic resonance imaging (MRI) contrast agents reported to be useful for the diagnosis of Alzheimer's disease and the treatment of Parkinson's and Alzheimer's disease.

Novartis AG has disclosed neuraminidase inhibitors acting as viral replication inhibitors reported to be useful for the treatment of influenza.

Medshine Discovery Inc. has presented heteroaryl-3-piperidinediones acting as proteolysis targeting chimera (PROTAC) compounds comprising cereblon (CRBN) E3 ubiquitin ligase-binding moiety covalently linked to eukaryotic peptide chain release factor GTP-binding subunit ERF3A (GSPT1)-targeting moiety through linker.

Selmod GmbH has identified compounds reported to be useful for the treatment of fungal infections.

Carna Biosciences Inc. has synthesized 1,2-diaminobenzimidazole derivatives acting as stimulator of interferon genes protein (STING) antagonists reported to be useful for the treatment of cancer, viral infection, neurodegeneration and autoimmune, inflammatory, metabolic, eye and cardiovascular disorders, among others.

Astellas Pharma Inc. and Kotobuki Pharmaceutical Co. Ltd. have divulged annulated pyridazines...