Korea University Research and Business Foundation (KURBF) has disclosed peptides acting as apoptosis inducers reported to be useful for the treatment of cancer.
West China Hospital, Sichuan University has described heteroatom-substituted aromatic compounds reported to be useful for the treatment of pain and as general anesthetics.
Sunshine Lake Pharma Co. Ltd. has divulged benzazepine heterocyclic compounds acting as nuclear receptor RORγT (T cell-specific isoform 2) agonists reported to be useful for the treatment of cancer, rheumatoid arthritis, psoriasis, asthma, systemic lupus erythematosus, multiple sclerosis, inflammatory bowel disease and Kawasaki disease, among others.
Shanghai Allist Pharmaceuticals Co. Ltd. has synthesized nitrogen-containing heterocyclic compounds acting as GTPase KRAS (G12D mutant) and (G12V mutant) inhibitors reported to be useful for the treatment of cancer.
Tyra Biosciences Inc. has described indazole compounds acting as fibroblast growth factor receptors (FGFR) inhibitors reported to be useful for the treatment of cancer.
Tuojie Biotech (Shanghai) Co. Ltd. has divulged cyclin-dependent kinase 2 (CDK2)/cyclin E inhibitors reported to be useful for the treatment of cancer and immunological disorders.
Uppthera Inc. has identified proteolysis targeting chimera (PROTAC) compounds comprising an E3 ubiquitin ligase-binding agent coupled to serine/threonine-protein kinase PLK1 (STPK13) targeting moiety through a linker, acting as novel PLK1 protein degradation-inducing compounds with use for the treatment of cancer and neurological disorders.
Shanghai Institute of Materia Medica of the Chinese Academy of Sciences and Wuhan Institute of Virology of the Chinese Academy of Sciences have synthesized amide compounds reported to be useful for the treatment of dengue virus infection, skin inflammation, inflammatory joint disease, inflammatory bowel disease and autoimmune disease.
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