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BioWorld - Sunday, June 22, 2025
Home » Topics » Regulatory » Patents

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Cancer

New MALT1 inhibitors disclosed in Nippon Shinyaku patent

April 29, 2025
Nippon Shinyaku Co. Ltd. has divulged azaindole compounds acting as mucosa-associated lymphoid tissue lymphoma translocation protein 1 (MALT1) inhibitors reported to be useful for the treatment of cancer, multiple sclerosis, rheumatoid arthritis, psoriasis, spinal cord injury, Behçet’s disease, atopic dermatitis and idiopathic pulmonary fibrosis, among others.
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Cancer

Pharmaengine describes new PKMYT1 inhibitors

April 29, 2025
Pharmaengine Inc. has identified Myt1 kinase (PKMYT1) inhibitors reported to be useful for the treatment of cancer.
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Infection

Nuvobio divulges new peptides to treat C. neoformans infection

April 29, 2025
Nuvobio Corp. has synthesized peptides reported to be useful for the treatment of Cryptococcus neoformans infection.
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Inflammatory

Suzhou Ark Biopharmaceutical patents new PDE4 inhibitors

April 29, 2025
Suzhou Ark Biopharmaceutical Co. Ltd. has disclosed phosphodiesterase PDE4 inhibitors.
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Musculoskeletal

Shanghai Qilu Pharmaceutical discovers new immunoproteasome inhibitors

April 28, 2025
Shanghai Qilu Pharmaceutical Research and Development Centre Ltd. has described immunoproteasome inhibitors reported to be useful for the treatment of systemic lupus erythematosus and arthritis.
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Cancer

New SSTR2 ligands disclosed in Qianhangjiang Pharmaceutical patent

April 28, 2025
Qianhangjiang Pharmaceutical Co. Ltd. has divulged somatostatin peptide analogues acting as somatostatin receptor type 2 (SSTR2) ligands reported to be useful for the treatment of cancer and acromegaly.
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Cancer

Summit Therapeutics describes new KRAS (G12D) inhibitors and degradation inducers

April 28, 2025
Summit Therapeutics Inc. has identified proteolysis targeting chimera (PROTAC) compounds comprising an E3 ubiquitin ligase binding moiety coupled to a GTPase KRAS (G12D) targeting moiety through a linker acting as KRAS (G12D) inhibitors and degradation inducers reported to be useful for the treatment of cancer.
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Cancer

Shanghai Jemincare Pharmaceuticals divulges new USP1 inhibitors

April 28, 2025
Shanghai Jemincare Pharmaceutical Co. Ltd. has synthesized ubiquitin carboxyl-terminal hydrolase 1 (USP1) inhibitors reported to be useful for the treatment of cancer.
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Cancer

Beijing Primegene Therapeutics patents new Nek7 inhibitors

April 28, 2025
Beijing Primegene Therapeutics Co. Ltd. has disclosed serine/threonine-protein kinase Nek7 inhibitors reported to be useful for the treatment of cancer, inflammatory bowel disease, stroke, osteoarthritis, multiple sclerosis, rheumatoid arthritis, atherosclerosis and Alzheimer’s disease, among others.
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Cancer

Pliant Therapeutics discovers new integrin αvβ1, αvβ6 and/or αvβ8 antagonists

April 25, 2025
Pliant Therapeutics Inc. has described integrin αvβ1, integrin αvβ6 and/or integrin αvβ8 antagonists reported to be useful for the treatment of cancer and fibrosis.
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