East China University of Science & Technology has described pteridinone derivatives acting as epidermal growth factor receptor (EGFR; HER1; erbB1) (mutant) inhibitors reported to be useful for the treatment of cancer.
China Pharmaceutical University has synthesized receptor-interacting serine/threonine-protein kinase 1 (RIPK1; RIP-1) inhibitors reported to be useful for the treatment of ischemic stroke, among others.
Janssen Pharmaceutica NV has disclosed IL-17A/IL-17 receptor A (IL-17RA) interaction modulators reported to be useful for the treatment of psoriasis, rheumatoid arthritis, radiographic axial spondyloarthritis (ankylosing spondylitis), multiple sclerosis, asthma and more.
The Chinese National Institute of Pharmaceutical R&D Co. Ltd. has described sulfonamide compounds acting as tyrosine-protein phosphatase non-receptor type 11 (PTPN11; PTP-2C; SHP-2) inhibitors reported to be useful for the treatment of diabetes, obesity, cancer, Noonan and LEOPARD syndromes.
Research at Enveric Biosciences Canada Inc. has led to the development of aminated psilocybin derivatives acting as 5-HT1A or 5-HT2A receptor modulators and reported to be useful for the treatment of psychiatric disorders.
Vifor Pharma Ltd. has identified solute carrier family 40 member 1 (SLC40A1; ferroportin) inhibitors reported to be useful for the treatment of iron metabolism disorders, among others.
Shionogi & Co. Ltd. has synthesized spiroheterocycle derivatives acting as 5-HT2A and 5-HT2C receptor antagonists and/or inverse agonists reported to be useful for the treatment of neurodegeneration.