Wigen Biomedicine Technology (Shanghai) Co. Ltd. has disclosed isocitrate dehydrogenase (NADP+) (IDPc, IDH1) mutant inhibitors reported to be useful for the treatment of cancer.
Beijing Innocare Pharma Tech Co. Ltd. has divulged heterocyclic compounds acting as son of sevenless homolog 1 (SOS1) inhibitors reported to be useful for treatment of cancer.
Jiangsu Chia Tai Tianqing Pharmaceutical Group Co. Ltd. and Medshine Discovery Inc. have identified benzoxazinone derivatives acting as mineralocorticoid receptor (MR) antagonists reported to be useful for the treatment of diabetic nephropathy.
Glaxosmithkline Intellectual Property Ltd. has synthesized cytochrome bc1 complex (complex III) (Plasmodium falciparum) inhibitors reported to be useful for the treatment of malaria.
Celgene Corp. has disclosed sphingosine 1-phosphate receptor 5 (S1PR5; EDG8) modulators reported to be useful for the treatment of Alzheimer's disease and multiple sclerosis.
Gruenenthal GmbH has described substituted pyrazole amides acting as sodium channel protein type 10 subunit α (SCN10A; Nav1.8) blockers reported to be useful for the treatment of pain.
Suzhou Spring-Sea Bio-Pharmaceuticals Co. Ltd. has divulged prodrugs of N4-hydroxycytidine (NHC) reported to be useful for the treatment of viral infections.
Tuojie Biotech (Shanghai) Co. Ltd. has identified mucosa-associated lymphoid tissue lymphoma translocation protein 1 (MALT1) inhibitors reported to be useful for the treatment of cancer, inflammation and autoimmune diseases.
National Institute of Pharmaceutical R&D Co. Ltd. has synthesized high affinity nerve growth factor receptor (NTRK1; TRKA) and its mutant inhibitors reported to be useful for the treatment of cancer.