Eleusis Therapeutics US Inc. has synthesized aryl-ring-substituted 3-phenylazetidines acting as 5-HT2 receptor ligands reported to be useful for the treatment of chronic pain, depression, atherosclerosis, chronic obstructive pulmonary disease, conjunctivitis, type 2 diabetes, multiple sclerosis and rheumatoid arthritis, among others.
Gilead Sciences Inc. has divulged thienopyrrole compounds acting as Toll-like receptor 7 (TLR7) and/or TLR8 antagonists reported to be useful for the treatment of systemic lupus erythematosus (SLE), cutaneous lupus erythematosus, lupus nephritis and inflammatory disorders, among others.
Medshine Discovery Inc. has identified imidazopyridine compounds acting as Bruton tyrosine kinase (BTK) inhibitors reported to be useful for the treatment of autoimmune diseases.
Novartis AG has synthesized heteroaryl aminopropanol derivatives acting as leukotriene A4 hydrolase (LTA4H; LTA4) inhibitors reported to be useful for the treatment of cancer, chronic obstructive pulmonary disease (COPD), psoriasis, sepsis, periodontal and autoimmune disease, cardiovascular and inflammatory disorders, among others.
Medshine Discovery Inc. and Jiangsu Chia Tai Tianqing Pharmaceutical Group Co. Ltd. have disclosed bicyclic substituted aromatic carboxylic acid compounds acting as complement factor B (CFB) inhibitors reported to be useful for the treatment of Parkinson's disease.
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