Seecure Taiwan Co. Ltd. has disclosed compounds reported to be useful for the treatment or diagnosis of cancer, autoimmune diseases and atherosclerosis.
Medshine Discovery Inc. has described gonadotropin-releasing hormone receptor (GnRHR) antagonists reported to be useful for the treatment of prostate cancer.
Bayer AG has synthesized new furoindazole derivatives acting as G protein-coupled receptor 84 (GPR84) antagonists reported to be useful for the treatment of inflammation, metabolic disorders, autoimmune and lung diseases, among others.
Medshine Discovery Inc. has patented new sulfinylpyridine-containing nonreceptor tyrosine-protein kinase TYK2 inhibitors expected to be useful for the treatment of Crohn's disease, systemic lupus erythematosus, psoriasis, psoriatic arthritis and ulcerative colitis.
McMaster University has identified antibody-recruiting molecules (ARMs) consisting of human coronavirus (SARS-CoV-2) proteins targeting domain covalently bound to an antibody-binding terminus (recruiting anti-DNP antibodies) through a linker.
Bayer AG has discovered P2X purinoceptor 3 (P2RX3) antagonists reported to be useful for the treatment of overactive bladder, chronic cough, endometriosis, cancer, heart failure, irritable bowel syndrome with diarrhea, pain and sleep apnea, among others.
University of Chicago has described estrogen receptor (ER)-α antagonists reported to be useful for the treatment of cancer, fibroids, uterine (myoma), hormone replacement therapy, menopause, obesity, osteoporosis and atrophic vulvovaginitis.
The Royal Veterinary College has presented drug conjugates comprising hyaluronan (HA) synthesis inhibitors covalently bonded to betaine reported to be useful for the treatment of chondrosarcoma and osteoarthritis.