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BioWorld - Thursday, February 26, 2026
Home » Topics » Regulatory » Patents

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Cancer

The Ohio State University divulges new MPS1 inhibitors

Aug. 13, 2025
The Ohio State University has synthesized dual specificity protein kinase TTK (MPS1; MPS1L1) inhibitors reported to be useful for the treatment of cancer.
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Neurology/psychiatric

Stanford University patents new LRRK2 inhibitors

Aug. 13, 2025
Stanford University has disclosed leucine-rich repeat kinase 2 (LRRK2; dardarin) inhibitors reported to be useful for the treatment of cancer, Crohn’s disease, leprosy, neurodegeneration, immunological disorders, Parkinson’s disease and Alzheimer’s disease.
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Endocrine/metabolic

Insilico Medicine discovers new glucocorticoid receptor antagonists

Aug. 12, 2025
Insilico Medicine Ltd. has described glucocorticoid receptor (GR) antagonists reported to be useful for the treatment of Cushing’s syndrome, Addison’s disease, osteoporosis, rheumatoid arthritis, asthma, rhinitis, allergy and skin lesions.
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Infection

New PB2 inhibitors disclosed in Innovstone Therapeutics patent

Aug. 12, 2025
Innovstone Therapeutics Ltd. has divulged prodrugs of deuterated baloxavir marboxil derivatives acting as polymerase basic protein 2 (PB2) (influenza virus) inhibitors reported to be useful for the treatment of influenza A, influenza B and influenza C viral infections.
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Cancer

Jiangsu Vcare Pharmatech describes new Mat2A inhibitors

Aug. 12, 2025
Jiangsu Vcare Pharmatech Co. Ltd. has identified S-adenosylmethionine synthase isoform type-2 (Mat2A) inhibitors reported to be useful for the treatment of cancer.
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Cancer

Zhejiang University divulges new isoquinoline derivatives

Aug. 12, 2025
Zhejiang University has synthesized isoquinoline derivatives reported to be useful for the treatment of cancer, infections, autoimmune disease, and cardiovascular, cerebrovascular and Inflammatory disorders.
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Cancer

LG Chem patents new BRD4 BD1 and CBP inhibitors

Aug. 12, 2025
LG Chem Ltd. has disclosed bromodomain-containing protein 4 (BD1 domain) (BRD4 BD1) and CREB-binding protein (CREBBP; CBP) inhibitors reported to be useful for the treatment of cancer, inflammatory disorders and autoimmune disease.
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Neurology/psychiatric

Temple University discovers new antioxidants and NRF2 activators

Aug. 11, 2025
Temple University has described compounds acting as antioxidants and nuclear factor erythroid 2-related factor 2 (NFE2L2; NRF2) activators reported to be useful for the treatment of Alzheimer’s disease, Parkinson’s disease, Huntington’s disease, cerebral palsy, epilepsy and multiple sclerosis.
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Cancer

New WRN inhibitors disclosed in Chengdu Chipscreen Pharmaceutical patent

Aug. 11, 2025
Chengdu Chipscreen Pharmaceutical Ltd. has divulged Werner syndrome ATP-dependent helicase (WRN; RECQ3; RECQL2) inhibitors reported to be useful for the treatment of cancer.
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Respiratory

Open Source Therapeutics describes new EPHX2 inhibitors

Aug. 11, 2025
Open Source Therapeutics Co. Ltd. has identified bifunctional epoxide hydrolase 2 (EPHX2; sEH) inhibitors reported to be useful for the treatment of chronic obstructive pulmonary disease (COPD), Alzheimer’s disease, epilepsy, hypertension, psoriasis, rheumatoid arthritis, stroke and ulcerative colitis, among others.
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