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BioWorld - Thursday, December 25, 2025
Home » Topics » Asia-Pacific » Japan

Japan
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Elderly man with clenched hands holding head

Three strikes for Otsuka’s AVP-786 as it fails in AD-related agitation

Feb. 13, 2024
By Tamra Sami
Otsuka Pharmaceutical Co. Ltd.’s AVP-786 missed the primary endpoint for a third time in a phase III trial for agitation associated with dementia due to Alzheimer’s disease (AD). Two previous phase III trials also failed to show statistical significance for AVP-786.
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Masayo Takahashi, CEO, Vision Care
Ocular

Newco news: Vision Care’s iPS retinal cells primed for global market

Feb. 13, 2024
By Tamra Sami
Vision Care Group CEO Masayo Takahashi led the world's first clinical study of a retinal cell transplant derived from induced pluripotent stem cells (iPS cells) in 2014 when she led the Laboratory for Retinal Regeneration at Japan’s Riken Center for Biosystems Dynamics Research. In 2019, she founded Vision Care and subsequently founded two subsidiary companies dedicated to developing cell and gene therapies.
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3D dollar sign

Kyowa pays $100M up front for Bridgebio’s infigratinib in Japan

Feb. 8, 2024
By Marian (YoonJee) Chu
Palo Alto, Calif.-based Bridgebio Pharma Inc. will hand over development and sales of its rare bone growth disorder therapy, infigratinib, in Japan to Kyowa Kirin Co. Ltd. under its latest exclusive licensing deal.
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Polycythemia vera illustration

Takeda and Protagonist ink global license and development deal worth $1.7B for hematology asset rusfertide

Feb. 6, 2024
By Tamra Sami
Takeda Pharmaceutical Co. Ltd. and Protagonist Therapeutics Inc. have inked a global development and commercialization deal worth up to $1.7 billion for Protagonist’s rusfertide for treatment of polycythemia vera (PV), a rare and chronic blood disorder affecting bone marrow.
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3D illustration of heart cross section

Bridgebio seeks Japan approval of acoramidis for rare heart disease

Feb. 5, 2024
By Marian (YoonJee) Chu
Armed with strong phase III safety data in Japanese patients, Palo Alto, Calif.-based Bridgebio Pharma Inc. is planning to file for Japan approval of its investigational drug acoramidis for a rare heart disorder.
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3D illustration of heart cross section

Bridgebio seeks Japan approval of acoramidis for rare heart disease

Feb. 5, 2024
By Marian (YoonJee) Chu
Armed with strong phase III safety data in Japanese patients, Palo Alto, Calif.-based Bridgebio Pharma Inc. is planning to file for Japan approval of its investigational drug acoramidis for a rare heart disorder.
Read More
Polycythemia vera illustration

Takeda and Protagonist ink global license and development deal worth $1.7B for hematology asset rusfertide

Feb. 1, 2024
By Tamra Sami
Takeda Pharmaceutical Co. Ltd. and Protagonist Therapeutics Inc. have inked a global development and commercialization deal worth up to $1.7 billion for Protagonist’s rusfertide for treatment of polycythemia vera (PV), a rare and chronic blood disorder affecting bone marrow.
Read More
Masayo Takahashi, CEO, Vision Care

Vision Care’s iPS retinal cells primed for global market

Jan. 30, 2024
By Tamra Sami
Vision Care Group CEO Masayo Takahashi led the world's first clinical study of a retinal cell transplant derived from induced pluripotent stem cells (iPS cells) in 2014 when she led the Laboratory for Retinal Regeneration at Japan’s Riken Center for Biosystems Dynamics Research. In 2019, she founded Vision Care and subsequently founded two subsidiary companies dedicated to developing cell and gene therapies.
Read More
TUS infographic

New non-invasive imaging tech visualizes liver fat

Jan. 26, 2024
By Marian (YoonJee) Chu
A new study published by researchers from the Tokyo University of Science (TUS) unveiled a new machine learning-aided, non-invasive imaging framework for rapid liver lipid visualization, which could help diagnose and treat steatotic liver diseases (SLD).
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China’s Ji Xing signs flurry of Asian deals to advance cardiovascular pipeline and global ambitions

Jan. 16, 2024
By Tamra Sami
Shanghai-based Ji Xing Pharmaceuticals has signed a number of licensing deals over the last week for China rights to cardiovascular drugs to advance its pipeline and its global ambitions, partnering most recently with Tokyo-based TMS Co. Ltd. after the Chinese company acquired global rights for TMS-007 (also known as BIIB-131) from Biogen Inc.
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