Donghua University and Rudjer Boskovic Institute (RBI) scientists have described the synthesis of a preclinical photosensitizer for anticancer...

Researchers from Alzecure Pharma AB have presented preclinical data on a novel TrkA negative allosteric modulator (NAM), AC-0027838, for...

Impairment in the functionality of the adipose tissue is crucial for obesity-related metabolic comorbidities and may trigger the onset of type 2 diabetes. The adipose tissue has been proposed as a main contributor of circulating miRNAs (miRNAs), but has not yet been characterized for these markers.

Understanding how alternative splicing is regulated and how it contributes to disease pathogenesis might open new therapeutic options for the treatment of diabetic nephropathy (DN). Bcl-2-like protein 1 (BCL2L1), also known as BCLX, for which two alternative splicing forms (Bcl-xL and Bcl-xS) have been seen to have antagonistic effects.

Recently, extracellular matrix remodeling has emerged as a key element involved in the...

The 2-C-methyl-D-erythritol 4-phosphate (MEP) pathway, a metabolic pathway for the...

GSK plc and Bioversys AG have described the development of ethionamide boosters...

Researchers have designed a 3D model of lung cancer that is composed of bronchial epithelial, fibroblasts, epithelial, lung adenocarcinoma and immune cells grown in different layers in a matrigel.