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BioWorld Science, Cancer
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Cancer

Hangzhou Raygene Pharmaceutical describes new benzotriazine dioxide compounds

Nov. 6, 2025
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Hangzhou Raygene Pharmaceutical Co. Ltd. has identified benzotriazine dioxide compounds reported to be useful for the treatment of cancer.
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Cancer

Scinnohub patents new RET inhibitors

Nov. 6, 2025
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Scinnohub Pharmaceutical Co. Ltd. has disclosed compounds reported to be useful for the treatment of cancer and inflammatory diseases.
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Cancer cell in the cross-hairs
Cancer

Acrivon Therapeutics reports preclinical data on ACR-2316

Nov. 6, 2025
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Acrivon Therapeutics Inc. has developed a new WEE1/PKMYT1 inhibitor, ACR-2316, to overcome the limitations observed with previous WEE1 and PKMYT1 inhibitors in the treatment of cancer.
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Cancer

Accutar presents development of PI3Kα degrader-antibody conjugates

Nov. 6, 2025
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Accutar Biotechnology Inc. recently presented preclinical data on AC-4847, a first-in-class PI3Kα-targeting degrader-antibody conjugate (DAC) designed for selective treatment of PI3Kα-driven cancers.
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3D rendering of an antibody drug conjugate
Immuno-oncology

CBB-120 shows potent TROP2 targeting with improved safety margin

Nov. 6, 2025
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Researchers at Crossbridge Bio Inc. have conducted preclinical evaluation of CBB-120, a novel TROP2-directed dual-payload ADC designed to combine TOP1i and ATR inhibitor (ATRi) mechanisms for enhanced therapeutic efficacy.
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Cancer

Hangzhou Baicreat Pharma-Tech describes new POLθ inhibitors

Nov. 5, 2025
Hangzhou Baicreat Pharma-Tech Co. Ltd. has identified DNA polymerase θ (POLθ) inhibitors reported to be useful for the treatment of cancer.
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Cancer

Shanghai Apeiron Biotechnology patents new PRMT5 degradation inducers

Nov. 5, 2025
Shanghai Apeiron Biotechnology Co. Ltd. has disclosed proteolysis targeting chimeras (PROTACs) reported to be useful for the treatment of cancer.
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Cancer

Prelude signs option deal, prioritizes JAK2 and KAT6A programs

Nov. 5, 2025
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Prelude Therapeutics Inc. has outlined its plans to prioritize programs within its pipeline and announced an exclusive option agreement with Incyte Corp.
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3D illustration demonstrating antibody-drug conjugate.
Immuno-oncology

Bispecific antibody-drug conjugate Gensci-143 shows promise in solid tumors

Nov. 5, 2025
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Changchung Genescience Pharmaceutical Co. Ltd., reported effects of the bispecific antibody-drug conjugate (ADC) of Gensci-143, is in metastatic castration-resistant prostate cancer (mCRPC) and other solid tumors.
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Immuno-oncology

Glycan-targeting ADC shows preclinical activity against HER2-low gastric cancer

Nov. 5, 2025
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Advanced gastric cancer continues to pose a significant medical challenge because of the scarcity of effective treatments and the frequent development of resistance to available drugs.
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