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BioWorld - Wednesday, April 29, 2026
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Home » Topics » BioWorld Science, Cancer

BioWorld Science, Cancer
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Cancer

Hangzhou Baicreat Pharma-Tech describes new POLθ inhibitors

Nov. 5, 2025
Hangzhou Baicreat Pharma-Tech Co. Ltd. has identified DNA polymerase θ (POLθ) inhibitors reported to be useful for the treatment of cancer.
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Cancer

Shanghai Apeiron Biotechnology patents new PRMT5 degradation inducers

Nov. 5, 2025
Shanghai Apeiron Biotechnology Co. Ltd. has disclosed proteolysis targeting chimeras (PROTACs) reported to be useful for the treatment of cancer.
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Cancer

Prelude signs option deal, prioritizes JAK2 and KAT6A programs

Nov. 5, 2025
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Prelude Therapeutics Inc. has outlined its plans to prioritize programs within its pipeline and announced an exclusive option agreement with Incyte Corp.
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3D illustration demonstrating antibody-drug conjugate.
Immuno-oncology

Bispecific antibody-drug conjugate Gensci-143 shows promise in solid tumors

Nov. 5, 2025
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Changchung Genescience Pharmaceutical Co. Ltd., reported effects of the bispecific antibody-drug conjugate (ADC) of Gensci-143, is in metastatic castration-resistant prostate cancer (mCRPC) and other solid tumors.
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Immuno-oncology

Glycan-targeting ADC shows preclinical activity against HER2-low gastric cancer

Nov. 5, 2025
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Advanced gastric cancer continues to pose a significant medical challenge because of the scarcity of effective treatments and the frequent development of resistance to available drugs.
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Cancer cells being destroyed by immunotherapy
Immuno-oncology

Leukogene’s LTI-214 designated orphan drug for AML

Nov. 5, 2025
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Leukogene Therapeutics Inc.’s lead product candidate LTI-214 (M2T-CD33) has been awarded orphan drug designation by the FDA for the treatment of acute myeloid leukemia (AML).
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Cancer

Innocare Pharma divulges new CBLB inhibitors

Nov. 4, 2025
Beijing Innocare Pharma Tech Co. Ltd. has synthesized E3 ubiquitin-protein ligase CBL-B (CBLB) inhibitors reported to be useful for the treatment of cancer.
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Concept art for targeting cancer
Cancer

Astellas’ CRBN-based protein degrader inhibits KRAS G12D tumor growth

Nov. 4, 2025
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Researchers at Astellas Pharma Inc. have reported preclinical efficacy data of ASP-4396, a KRAS G12D degrader.
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Acute myeloid leukemia
Immuno-oncology

Evaxion unveils EVX-04 for acute myeloid leukemia

Nov. 4, 2025
No Comments
Evaxion A/S has unveiled EVX-04, an AI-designed precision cancer vaccine candidate being developed for acute myeloid leukemia (AML).
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Cancer

Covalent p53 activator shows activity in Y220C-mutant models

Nov. 4, 2025
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At the AACR-NCI-EORTC International Conference on Molecular Targets and Cancer Therapeutics, Frontier Medicines Corp. presented a first-in-class covalent activator of p53 Y220C with high potency and selectivity in restoring p53 tumor suppressor function.
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