There is a need of better markers that reflect key mechanisms involved in diabetic kidney disease (DKD). In a new study, investigators have identified increased concentrations of neuroblastoma suppressor of tumorigenicity 1 (NBL1) as a strong and independent predictor of progression to end-stage kidney disease (ESKD) in patients with diabetes.
Breast cancer progression depends on the interaction between the proliferating breast cancer cells and the biochemical and biophysical properties of the extracellular matrix (ECM).
Researchers presented data from a study that aimed to investigate the mechanism by which extracellular vesicle (EV)-associated miRNAs are involved in the activation of autophagy and the development of chemoradiation resistance in advanced non-small cell lung cancer (NSCLC).