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BioWorld - Thursday, January 22, 2026
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Radiopharmaceutical illustration
Cancer

SK Biopharmaceuticals in-licenses radiopharmaceutical WT-7695

Nov. 27, 2025
No Comments
SK Biopharmaceuticals Co. Ltd. has signed a license agreement with the Wisconsin Alumni Research Foundation (WARF) to acquire rights to WARF’s WT-7695, a preclinical-stage radiopharmaceutical therapy candidate developed in collaboration with the University of Wisconsin-Madison.
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Illustration of pink and blue antibodies
Endocrine/metabolic

CSPC’s JMT-206 cleared to enter clinic in China for obesity

Nov. 27, 2025
No Comments
CSPC Pharmaceutical Group Ltd. has gained clinical trial clearance from China’s National Medical Products Administration (NMPA) for JMT-206 for weight management in individuals with obesity or overweight and at least one weight-related comorbidity.
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3D rendering of prion structure
Neurology/psychiatric

Epigenetic technology could eliminate misfolded prion proteins

Nov. 27, 2025
By Mar de Miguel
No Comments
The number of deaths caused by prion diseases reaches about 30,000 annually. Only 5 months pass from the diagnosis of seemingly healthy patients to the fatal outcome of this neurodegenerative condition, and just 1 month until quality of life is completely lost. Removing the brain protein that causes this genetic or infectious disorder could be achieved thanks to new gene-silencing techniques. At a special meeting of the American Society of Gene & Cell Therapy, in “AAV-mediated epigenetic editing for prion disease,” Sonia Vallabh presented not just the data of her research, but the impact of this disease on her family and on herself.
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Illustration of cancer tumor
Drug design, drug delivery & technologies

Myrio first to develop binders with high affinity/specificity

Nov. 26, 2025
By Tamra Sami
No Comments
Myrio Therapeutics Pty Ltd. has been able to accomplish something no other company has yet been able to crack: to develop binders where both the affinity and the specificity can be increased.
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Dermatologic

Samsung Life Public Welfare Foundation discovers new TLR signaling inhibitors

Nov. 26, 2025
Samsung Life Public Welfare Foundation has described peptides acting as Toll-like receptor (TLR) signaling inhibitors and antioxidants reported to be useful for the treatment of cancer as well as immunological, dermatological and inflammatory disorders.
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Immune

New SIK inhibitors disclosed in Insilico Medicine patent

Nov. 26, 2025
Insilico Medicine IP Ltd. has divulged serine/threonine-protein salt-inducible kinase (SIK) inhibitors reported to be useful for the treatment of autoimmune disease, cancer, metabolic diseases, transplant rejection, and cardiovascular, dermatological, inflammatory and respiratory disorders, among others.
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Cancer

Chengdu Chipscreen Pharmaceutical describes new Mat2A inhibitors

Nov. 26, 2025
Chengdu Chipscreen Pharmaceutical Ltd. has identified S-adenosylmethionine synthase isoform type-2 (Mat2A) inhibitors reported to be useful for the treatment of cancer.
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Neurology/psychiatric

Biohaven Therapeutics divulges new PKM2 activators

Nov. 26, 2025
Biohaven Therapeutics Ltd. has synthesized pyruvate kinase M2 (PKM2) activators reported to be useful for the treatment of age-related macular degeneration, amyotrophic lateral sclerosis, multiple sclerosis, retinitis pigmentosa and fibrosis.
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Cancer

Nikang Therapeutics patents new CDK2 and CDK4 degradation inducers

Nov. 26, 2025
Nikang Therapeutics Inc. has disclosed proteolysis targeting chimera (PROTAC) compounds comprising an E3 ubiquitin ligase-binding moiety coupled to a cyclin-dependent kinase 2 (CDK2)- and/or CDK4-targeting moiety through a linker reported to be useful for the treatment of cancer.
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Bladder
Cancer

New FGFR3 inhibitors offer best-in-class selectivity, potency

Nov. 26, 2025
No Comments
FGFR3 genomic alterations, including S249C as the most common, are recognized oncogenic drivers in 10%-60% of bladder cancers depending on the disease stage. Onco3r Therapeutics BV recently reported the identification of a novel series of highly potent, isoform-selective small-molecule FGFR3 inhibitors.
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