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Other news to note for Jan. 24, 2024

Jan. 24, 2024
Additional early-stage research and drug discovery news in brief, from: IGC Pharma.
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Infection

Bioversys discovers new compounds for bacterial infections and skin inflammation

Jan. 23, 2024
Bioversys AG has described 3-(phenylsulfonyl)-[1,2,3]triazolo[1,5a]quinazolin-5(4h)-one derivatives with the ability to interact with accessory gene regulator A (AgrA) and inhibit the expression of AgrA-regulated virulence factors reported to be useful for the treatment of bacterial infections and skin inflammation.
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Infection

Scripps Research Institute presents new compounds to treat malaria

Jan. 23, 2024
Scripps Research Institute has divulged compounds reported to be useful for the treatment of malaria.
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Neurology/Psychiatric

Dana-Farber Cancer Institute describes new HDAC3 degraders

Jan. 23, 2024
Dana-Farber Cancer Institute Inc. has identified proteolysis targeting chimera (PROTAC) compounds comprising a Von Hippel-Lindau disease tumor suppressor (VHL) ligase binding moiety covalently bonded to a histone deacetylase (HDAC) targeting moiety through a linker.
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Cancer

Medshine Discovery divulges new PRMT5 inhibitors

Jan. 23, 2024
Medshine Discovery Inc. has synthesized amino-substituted heteroaryl derivatives acting as protein arginine N-methyltransferase 5 (PRMT5) inhibitors reported to be useful for the treatment of cancer.
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HIV/AIDS

Gilead Sciences patents new compounds to treat HIV infection

Jan. 23, 2024
Gilead Sciences Inc. has disclosed compounds reported to be useful for the treatment of HIV infection.
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T cells
Immuno-oncology

CDR-Life’s MAGE-A4 T-cell engager cleared to enter clinic for solid tumors

Jan. 23, 2024
CDR-Life Inc. has announced FDA clearance of an IND application for CDR-404, its lead program in development as a precision immunotherapy for solid tumors.
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Endocrine/Metabolic

GC Biopharma’s ERT GC-1130A designated orphan drug in EU for MPS IIIA

Jan. 23, 2024
The EMA has awarded orphan drug designation to GC Biopharma Corp.’s intracerebroventricular enzyme replacement therapy (ERT) candidate, GC-1130A, for mucopolysaccharidosis type IIIA (MPS IIIA, Sanfilippo syndrome type A), developed in collaboration with Novel Pharma Inc.
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3d illustration of ovarian cancer
Immuno-oncology

NK Celltech announces US IND clearance for NK cell therapy NK-010

Jan. 23, 2024
NK Celltech Co. Ltd. has announced FDA clearance for a clinical trial of NK-010, a nongenetically modified allogeneic peripheral blood natural killer (NK) cell drug.
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RNA virus illustration
Infection

New stapled lipopeptide platform offers pan-inhibitors of SARS-CoV-2 and other viruses

Jan. 23, 2024
Several highly pathogenic viruses, including SARS-CoV-2, share a conserved mechanism of infection via the fusion of the viral and host membranes employing a six-helix bundle (6-HB) heptad repeat.
Read More
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