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Home » Topics » BioWorld, Analysis and data insight

BioWorld, Analysis and data insight
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Biopharma deals 1Q25

Biopharma M&As plunge in Q1, while $66.86B in deals beats 2024 average

April 17, 2025
By Amanda Lanier
Biopharma deal value declined in the first three months of 2025 compared to the previous quarter, but remained above the 2024 quarterly average of $57.63 billion. In the first quarter (Q1), biopharma deals totaled $66.86 billion across 330 transactions, a decrease from $80.65 billion in Q4 2024, which saw 372 deals. However, this was a significant value increase from Q1 2024, when deals amounted to $44.32 billion across 376 transactions.
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Biggest gainers and losers for April 7-11, 2025

April 14, 2025
The top 10 biopharma stock gainers and losers for the week.
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Biopharma money raised: Jan. 1-April 10, 2025

April 11, 2025
Year-to-date money raised in public, private and other financings of biopharma companies.
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Money raised by biopharma

April 11, 2025
Total raised in public, private and other financings of biopharma companies, comparing 2019-2024.
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Concept of business partnership
Biopharma deals March 2025

Ten March deals passed $1B, totaling $25.31B in value

April 11, 2025
By Amanda Lanier
Biopharma dealmaking surged in the first quarter of 2025, totaling $66.86 billion, well ahead of the $44.16 billion recorded in the same period last year. March contributed $29.48 billion to the total, a 237% increase from February’s $8.76 billion and closely matching January’s $28.63 billion.
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Coin stacks layered with charts
Biopharma financings 1Q25

Biopharma sees Q1 financings pullback, but private funding climbs

April 11, 2025
By Amanda Lanier
Biopharma companies brought in $13.08 billion in financing during the first quarter (Q1) of 2025, marking a significant drop from every quarter of 2024. The number of financings also declined, with 239 transactions completed in Q1 this year, down from a quarterly average of approximately 299 deals in 2024.
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Bradley Burnam, CEO, Turn Therapeutics

Spevigo so-so, innovator takes another Turn at IL-36 in eczema

April 11, 2025
By Randy Osborne
With a promising IL-36 inhibitor for atopic dermatitis (AD, or eczema) at the phase II stage, Turn Therapeutics Inc. has gained $75 million in post-public commitments and meanwhile is pursuing a grassroots strategy to keep the coffers in balance.
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Illustration of interleukin-2 protein structure

IL-2 ADding contenders in eczema strategy

April 10, 2025
By Randy Osborne
The sparsity of mid-to-late stage prospects in atopic dermatitis (AD, or eczema) – which has proved an especially challenging indication – plus some newsmaking fizzles in the space have caused developers to probe new targets with particular intensity. Most popular approaches thus far involve IL-4, IL-13, thymic stromal lymphopoietin and JAK. Developers have stumbled for varying reasons such as high placebo response rates, safety or lack of clinical proof of concept. Among the potential AD rescuers is Nektar Therapeutics Inc. with rezpegaldesleukin (rezpeg), which takes aim at IL-2.
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Telitacicept packaging

Remegen’s lupus drug surfaces with phase III myasthenia gravis data

April 9, 2025
By Marian (YoonJee) Chu
Remegen Co. Ltd. emerged as a surprise challenger in the generalized myasthenia gravis space, unveiling positive phase III data of its China-approved lupus drug, telitacicept (RCT-18; Tai’ai), in the rare autoimmune neuromuscular disorder at the 2025 American Academy of Neurology conference.
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Layered  charts

Trial misses sink cancer stocks in Q1: Mersana, Cargo, Mural fall

April 8, 2025
By Amanda Lanier
The BioWorld Cancer Index ended the first quarter (Q1) of 2025 down 4.74%, retreating after a promising start that saw the index rise 5.78% by the end of January. In the first quarter, 20 stocks declined in value while just nine posted gains.
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