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BioWorld - Tuesday, June 23, 2026
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Financings for Nov. 19, 2025

Nov. 19, 2025
Biopharmas raising money in public or private financings, including: Angiex, Avanzanite, Bambusa, Fennec, Invivyd, Respirerx, Solve.
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Appointments and advancements for Nov. 19, 2025

Nov. 19, 2025
New hires and promotions in the biopharma industry, including: Agenus, Akari, Apollomics, Medicinova, Nuvig, Serb, Zymeworks.
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Acute myeloid leukemia illustration

GSK, LTZ partner to develop myeloid cell engagers

Nov. 19, 2025
By Tamra Sami
No Comments
Immunotherapy-focused biotech company LTZ Therapetics Inc. and GSK plc are partnering to develop up to four potential first-in-class myeloid cell engagers using LTZ’s immune-engager platform to target blood cancers and solid tumors.
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Red CAR T cell on blue blackground

Tempest gains CAR Ts for 65% of the company; stock drops

Nov. 19, 2025
By Karen Carey
No Comments
Tempest Therapeutics Inc. entered definitive agreements approved by its board to acquire certain dual-targeting CAR T programs from Factor Bioscience Inc. and its affiliates in an all-stock transaction expected to close in early 2026.
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Probiotics, bacteria on white background

UK study reveals inconsistencies in global microbiome research

Nov. 19, 2025
By Nuala Moran
No Comments
The U.K. Medicines and Healthcare products Regulatory Agency is calling for unified standards to harmonize microbiome research, after revealing major inconsistencies in the results when labs around the world analyzed identical reference samples of gut bacteria.
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Lymph nodes and lymphatic vessels

Protara sees Chugai blue sky in LMs as phase II data strong

Nov. 19, 2025
By Randy Osborne
No Comments
Success in Japan may further bolster Protara Therapeutics Inc. in its push with TARA-002 in pediatric patients with macrocystic and mixed cystic lymphatic malformations (LMs), for which the New York-based firm disclosed interim results from an ongoing phase II trial.
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Money and pills

Partisan rhetoric heats up in Rx price-lowering jousting

Nov. 19, 2025
By Mari Serebrov
No Comments
In a verbal sparring over who can deliver the lowest drug prices in the U.S., several Senate Democrats are urging President Donald Trump to immediately release the list of second-round Medicare-negotiated drug prices, instead of doing what they characterize as “ambiguous” and “opaque” pricing deals with individual biopharma companies.
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Illustration of sickle-cell and normal red blood cells

Agios planning sNDA on mixed sickle cell data for mitapivat

Nov. 19, 2025
By Jennifer Boggs
No Comments
“Our goal is that by the end of this call, you’ll share our conviction in the totality of the data.” So said Agios Pharmaceuticals Inc. CEO Brian Goff as the company reported top-line data from its 52-week Rise Up trial testing mitapivat in sickle cell disease showing the oral pyruvate kinase activator hit statistical significance on one of two primary endpoints and two of three key secondary endpoints.
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Agios planning sNDA on mixed sickle cell data for mitapivat

Nov. 19, 2025
No Comments
A preview of the next edition of BioWorld, Nov. 19, 2025
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Gears traveling between drug capsule and head
Neurology/psychiatric

SfN 2025: How ‘latent’ sex differences can trip up drug discovery

Nov. 19, 2025
By Anette Breindl
No Comments
At the 2025 annual meeting of the Society for Neuroscience in San Diego this week, Catherine Woolley’s plenary lecture was an unusual combination of debunking and affirming the importance of sex differences in the brain.
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