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BioWorld - Tuesday, July 8, 2025
Breaking News: Trump administration impacts continue to roil the life sciences sectorBreaking News: Trump administration impacts continue to roil the life sciences sectorBreaking News: Self-amplifying mRNA technology underscored for next big pandemic
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Luye advances dual agonist for schizophrenia, Alzheimer’s

Aug. 13, 2024
By Tamra Sami
China’s National Medical Products Administration has cleared Luye Pharma Group Ltd.’s new schizophrenia candidate LY-03020 to enter phase I trials in China. Independently developed by Shanghai-based Luye, the new chemical entity is a dual agonist that targets both the trace amine-associated receptor 1 and the 5-HT2C receptor and is intended to treat schizophrenia and Alzheimer’s disease psychosis.
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Illustration of big fish eating three smaller fish
Biopharma deals July 2024

GSK, Novartis lead July deals as biopharma sector sees more than $20B for the month

Aug. 13, 2024
By Amanda Lanier
In July, biopharma deal values surged to $20.68 billion, a 61% increase from June's $12.82 billion. The boost pushed the total deal value for the first seven months of 2024 to $119.99 billion, marking the highest amount raised through July in BioWorld‘s records.
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Photo of jellyfish in aquarium lit by blue light
Aging

Jellyfish genes rejuvenate intestinal stem cells in fruit flies

Aug. 13, 2024
By Tamra Sami
Researchers in Japan were able to transfer genes from jellyfish into common fruit flies and discovered that the transferred gene suppressed an age-related intestinal issue in the flies. The findings suggest that studying genes specific to animals with high regenerative capability like jellyfish may uncover new mechanisms for rejuvenating stem cell function and extending the healthy lifespan of unrelated organisms.
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Illustration of Toxoplasma gondii tachyzoites
Drug design, drug delivery & technologies

Parasite could deliver therapeutic proteins to the brain

Aug. 13, 2024
By Mar de Miguel
Infection or cure? Scientists from Tel Aviv University and the University of Glasgow genetically modified the Toxoplasma gondii to bring a protein inside neurons. The novelty of using a protozoan that can travel from the gut to parasitize the CNS contrasts with the possibility of causing a disease. The scientists are already working on how to avoid it.
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Concept of business partnership

Genor wins $440M+ cancer drug deal with Third Rock/Two River firm

Aug. 13, 2024
By Marian (YoonJee) Chu
China’s Genor Biopharma Co. Ltd. agreed to out-license GB-261, its bispecific antibody candidate primarily targeting B-cell lymphomas, to TRC 2004 Inc., a U.S.-based newco co-founded by Third Rock Ventures LLC and Two River Group Holdings LLC.
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In the clinic for August 13, 2024

Aug. 13, 2024
Clinical updates, including trial initiations, enrollment status and data readouts and publications: Neuren Pharmaceuticals.
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Other news to note for August 13, 2024

Aug. 13, 2024
Biopharma happenings in Asia-Pacific including deals and partnerships, grants, preclinical data and other news in brief: Apotex, Daiichi Sankyo, Dong-A ST, Eyenovia, Formosa, Immunoforge, Kyowa Kirin, Medigene, Merck, Neurobo, Poxel, Newbridge, Sumitomo, Wuxi
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Regulatory actions for August 13, 2024

Aug. 13, 2024
Regulatory snapshots, including global submissions and approvals, clinical trial approvals and other regulatory decisions and designations: Masimo, Sofwave.
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As markets tumble, biotech expected to weather economic downturn

Aug. 6, 2024
By Amanda Lanier
Stocks tumbled on Aug. 5, with the Dow Jones Industrial Average falling more than 1,000 points amid a disappointing jobs report released by the U.S. Labor Department on Aug. 2. The BioWorld Stock Index, which tracks approximately 510 U.S. biopharma stocks, was up 17.27% for the year on July 26 before closing Aug. 5 up only 3.47%, representing a significant drop.
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Handshake with DNA, molecules

Otsuka to buy Boston chemoproteomics biotech for up to $1.1B

Aug. 6, 2024
By Marian (YoonJee) Chu
Tokyo-headquartered Otsuka Pharmaceutical Co. Ltd. said Aug. 1 that it will acquire Boston-based Jnana Therapeutics Inc. through a potential $1.125 billion M&A deal. Under the terms, Otsuka will work to close the transaction by the third quarter of 2024, with $800 million paid out to Jnana shareholders, along with up to $325 million in additional development and regulatory milestones payments.
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