Living in Stockholm, where the length of daylight ranges from about six hours at winter solstice to 18.5 hours at midsummer, pretty much guarantees a curiosity about how internal circadian rhythms are maintained.
The epithelial to mesenchymal transition (EMT) is a dedifferentiation process that occurs in tumor cells as they become more invasive. It has also been implicated as an important process in dedifferentiation that occurs during the generation of induced pluripotent stem cells (iPSCs).
In findings with implications for both drug discovery and cell fate, researchers have developed a method to map regulatory elements called enhancers to their target genes.
Weight loss is easy: eat fewer calories than you expend, and the body will compensate for the resulting energy deficit by burning fat. Unfortunately, weight loss is easy in the same way that Mark Twain described quitting smoking as easy – "I've done it a thousand times."
Of the two major DNA repair processes in the cell, homologous repair (HR) is slower and more precise than the quick, error-prone nonhomologous end joining (NHEJ).
ApoE variants are the strongest known genetic risk factor not just for Alzheimer's disease (AD), but for any disease. It was first described just about 25 years ago. "And I've worked on it since then," David Holtzman told BioWorld.