Scientists from the La Jolla Institute for Allergy & Immunology have discovered a major trigger for the airway remodeling that is one of the consequences of chronic asthma: LIGHT, a member of the tumor necrosis factor family of proteins.
One of the basic ways to classify antibodies is whether they are to self or nonself. But researchers from the University of California, San Diego and start-up Sialix Inc. have identified an antibody that is arguably both – and that might be useful as a cancer diagnostic or therapeutic.
Researchers at South San Francisco-based Genentech Inc., in collaboration with colleagues from Oxford University, have reported new insights into the p21-activated kinase (PAK).
Most scientists would think of stem cells as being on one end of a one-way street. A series of cell divisions can lead a stem cell down the path to a more restricted progenitor cell and ultimately, mature cell types. But a specific cell type cannot return spontaneously to its stem-like state.
Since induced pluripotent stem cells (iPSC) were first described in 2006, researchers have steadily chipped away at the number of transcription factors necessary to generate them.
In medical school, one of the things that students are taught is "when you hear hoofbeats, think horses, not zebras" – that is, common symptoms are most likely to be caused by common diseases. Or in practical terms, when you see a barfing child, think "stomach virus," not "brain tumor."
Thousand Oaks, Calif.- based biotech giant Amgen Inc. has taken several steps to expand its operations in Brazil: On Friday the company announced it acquired privately held Brazilian drugmaker Bergamo and reacquired the rights to several of its own products in Brazil.
In a study published this week, researchers from the Cleveland Clinic's Lerner Research Institute have discovered a strong new risk factor – the gut flora – for developing atherosclerotic heart disease and risk for heart attack, stroke and death.
