BioWorld looks at translational medicine, including: Base editor targets mitochondrial DNA; Everyone’s an immune cell; Brief anemia helps out nanoparticle drugs; Crosstalk between sex, stress hormones affects immunity; Astrocytes, endocannabinoids, metabolism cooperate to affect behavior; CDK-like kinase plays role in sensing pain; RNA editing restores Rett protein; Single-cell studies give insights into pulmonary fibrosis.
Keeping you up to date on recent developments in diagnostics, including: Diagnosing fatty liver disease; Assessing COVID-19 with lung ultrasound; Noncoding mutations contribute to heart disease.
Exercise is a powerful way to keep the elderly brain working well, not just in individuals that are healthy, but also in those with neurodegenerative disease. Even individuals with familial Alzheimer’s, though they will develop dementia regardless of whether they exercise or not, will have relatively better cognitive function if they exercise than if they don’t.
Forty years after HIV became a global pandemic, there are now more than 30 drugs approved to treat it. The National Institute of Allergy and Infectious Diseases’ director, Anthony Fauci, and clinical director, Clifford Lane, opined in the July 2, 2020, issue of The New England Journal of Medicine that “considering the spectacular scientific advances that have been made over nearly four decades, it is conceivable that with optimal implementation of available prevention strategies and treatments, the end of HIV/AIDS as a global pandemic will be attainable.”
A large epidemiological study published in the July 6, 2020, advance online issue of The Lancet found that most individuals who became infected with SARS-CoV-2 developed antibodies to the virus, confirming that infection usually results in at least a short-term immune response.
A large epidemiological study published in the July 6, 2020, advance online issue of The Lancet found that most individuals who became infected with SARS-CoV-2 developed antibodies to the virus, confirming that infection usually results in at least a short-term immune response.
Keeping you up to date on recent developments in cardiology, including: Potassium channel distancing fights stroke; Examining ischemic stroke in patients with COVID-19 vs. those with influenza; COVID-19 infects heart cells in lab dish.
Keeping you up to date on recent developments in diagnostics, including: Broad scale genomic testing for childhood illness; Deep learning model for cancer prognosis; Placenta attachment theory.
The checkpoint molecule CD47 has high hopes riding on it in oncology as being the innate immune equivalent of PD-1. Multiple companies are developing blockers against CD47 and/or its ligand, SIRPa, for the treatment of various tumors.
