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BioWorld - Wednesday, May 13, 2026
Home » Authors » Brian Orelli

Brian Orelli

Articles

ARTICLES

Futility at the interim: Biogen, Eisai pull plug on aducanumab for Alzheimer's

March 22, 2019
By Brian Orelli
Quarter after quarter, analysts have been pestering management on Biogen Inc.'s conference calls about whether there would be an interim analysis for the phase III program testing its Alzheimer's disease drug aducanumab.
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Use of CROs continues to grow, but companies remain skeptical

March 20, 2019
By Brian Orelli
The use of contract research organizations (CROs) by drug developers has continued to grow at an 8 percent clip annually since 2010, reaching an estimated $86 billion in 2018, according to a new report from the Tufts Center for the Study of Drug Development (CSDD).
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Reversal of fortunes: Phasebio jumps on early stage data

March 19, 2019
By Brian Orelli
With shares down more than 25 percent since its $5 IPO in October, Phasebio Pharmaceuticals Inc. saw its fortunes reverse with the help of phase I data for its reversal agent, PB-2452.
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Use of CROs continues to grow, but companies remain skeptical

March 18, 2019
By Brian Orelli
The use of contract research organizations (CROs) by drug developers has continued to grow at an 8 percent clip annually since 2010, reaching an estimated $86 billion in 2018, according to a new report from the Tufts Center for the Study of Drug Development (CSDD).
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Gtx-Oncternal hook up to form new public oncology company

March 8, 2019
By Brian Orelli
After Gtx Inc.'s only clinical candidate, selective androgen receptor modulator (SARM) enobosarm, failed to improve stress urinary incontinence in postmenopausal women, the company underwent a review of strategic alternatives. 
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Vertex batting 1,000 with 2 triples; bring in the 24-week closer data

March 7, 2019
By Brian Orelli
With positive phase III data in hand from its next-generation corrector, VX-659, Vertex Pharmaceuticals Inc. was in a no-lose situation as it released data from the cystic fibrosis (CF) phase III studies for its other next-generation corrector, VX-445.
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Pharma, VCs advise startups on best path for success

March 5, 2019
By Brian Orelli
SAN DIEGO – Advice for startups from pharma executives and venture capitalists abounded at the Biocom Global Life Science Partnering Conference last week.
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Pharma, VCs advise startups on best path for success

March 4, 2019
By Brian Orelli
SAN DIEGO – Advice for startups from pharma executives and venture capitalists abounded at the Biocom Global Life Science Partnering Conference last week.
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Agenus launches BEST: A crypto token for drugs

Feb. 25, 2019
By Brian Orelli
Blockchain has already infiltrated the drug industry, from tracking supply chain to information management system to cryptocurrencies to pay people for their genomic sequencing.
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Agenus launches BEST: A crypto token for drugs

Feb. 25, 2019
By Brian Orelli
Blockchain has already infiltrated the drug industry, from tracking supply chain to information management system to cryptocurrencies to pay people for their genomic sequencing. But now Agenus Inc. is looking to use the tracking technology to help fund drug development. The company announced plans to launch a Biotech Electronic Security Token (BEST), which will be tied to its anti-PD-1 antibody, AGEN-2034.
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View All Articles by Brian Orelli

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