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BioWorld - Wednesday, January 21, 2026
Home » Authors » John Fox

Articles by John Fox

Study suggests new approach to treating RAS-driven cancers

April 1, 2015
By John Fox
HONG KONG – In a landmark study, Singapore-based researchers have identified a novel kinase feedback loop controlling autophagy in common RAS-driven cancers and have shown that combining a kinase inhibitor with an agent that prevents autophagy may offer an effective new approach to treating such tumors.
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Study suggests new approach to treating RAS-driven cancers

April 1, 2015
By John Fox
HONG KONG – In a landmark study, Singapore-based researchers have identified a novel kinase feedback loop controlling autophagy in common RAS-driven cancers and have shown that combining a kinase inhibitor with an agent that prevents autophagy may offer an effective new approach to treating such tumors.
Read More

LDH inhibition shows promise for drug-resistant epilepsy

March 25, 2015
By John Fox
HONG KONG – Inhibition of lactate dehydrogenase (LDH) blocked the characteristic neuronal excitation seen in epileptic seizures in vitro and prevented such events in a mouse model of epilepsy in a study by Japanese pharmacologists, who also identified a promising new treatment for patients with drug-resistant epilepsy.
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LDH inhibition shows promise for drug-resistant epilepsy

March 24, 2015
By John Fox
HONG KONG – Inhibition of lactate dehydrogenase (LDH) blocked the characteristic neuronal excitation seen in epileptic seizures in vitro and prevented such events in a mouse model of epilepsy in a study by Japanese pharmacologists, who also identified a promising new treatment for patients with drug-resistant epilepsy.
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Pre-op ANP boosts lung cancer surgery survival

March 20, 2015
By John Fox
HONG KONG – Preoperative atrial natriuretic peptide (ANP) improved survival in lung cancer patients undergoing surgery and appeared to prevent cancer metastasis through prevention of vascular endothelial inflammation and adhesion in mice, Japanese researchers reported in the March 16, 2015, early edition of the Proceedings of the National Academy of Sciences.
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Return to pre-antibiotic era? AMR hits developing countries the hardest

March 11, 2015
By John Fox
HONG KONG – New antibiotic agents are urgently needed to overcome the burgeoning problem of antimicrobial resistance (AMR) in infectious bacteria, but novel agents alone may not be sufficient to prevent a return to the dark days of the pre-antimicrobial era, an infectious disease specialist has warned.
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Return to pre-antibiotic era? AMR hits developing countries hardest

March 10, 2015
By John Fox
HONG KONG – New antibiotic agents are urgently needed to overcome the burgeoning problem of antimicrobial resistance in infectious bacteria, but novel agents alone may not be sufficient to prevent a return to the dark days of the pre-antimicrobial era, an infectious disease specialist has warned.
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Researchers find a powerful new dengue neutralizing antibody

March 4, 2015
By John Fox
HONG KONG – A study led by Singaporean researchers has identified a potent new antibody against the dengue virus, a minimal amount of which is required to neutralize it, which is an important finding that may lead to the development of effective new treatments or vaccines.
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Researchers find a powerful new dengue neutralizing antibody

March 3, 2015
By John Fox
HONG KONG – A study led by Singaporean researchers has identified a potent new antibody against the dengue virus, a minimal amount of which is required to neutralize it, which is an important finding that may lead to the development of effective new treatments or vaccines.
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Common heart drug interactions traced to vitamin K: study

Feb. 25, 2015
By John Fox
HONG KONG — The results of a study by Japanese researchers from the University of Tokyo have helped to elucidate the previously unknown underlying mechanism whereby two commonly prescribed drugs in patients at risk for heart disease can adversely interact, a finding that could lead to improved clinical care of patients taking those medications.
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