A month after signing a billion-dollar deal with GlaxoSmithKline plc for elesclomol (formerly STA-4783), Synta Pharmaceuticals Corp. kicked off a pivotal Phase III trial of the drug in metastatic melanoma. (BioWorld Today)
In a deal that could top $440 million, Amicus Therapeutics Inc. teamed up with Shire Human Genetic Therapies Inc. on the ex-U.S. development and commercialization of Amicus's three lead pharmacological chaperone compounds for lysosomal storage disorders (LSDs): Amigal, Plicera and AT2220. (BioWorld Today)
In a deal that could top $440 million, Amicus Therapeutics Inc. teamed up with Shire Human Genetic Therapies Inc. on the ex-U.S. development and commercialization of Amicus's three lead pharmacological chaperone compounds for lysosomal storage disorders (LSDs): Amigal, Plicera and AT2220. (BioWorld Today)