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BioWorld - Monday, December 15, 2025
Home » Keywords » loss of function

Items Tagged with 'loss of function'

ARTICLES

Telomeres and DNA illustration

Tessellate signs $570M Boehringer deal targeting ALT-positive cancers

April 23, 2025
By Nuala Moran
Synthetic lethality specialist Tessellate Bio NV has closed its first deal, agreeing to a €500 million-plus (US$570 million) research and license agreement with Boehringer Ingelheim GmbH, to develop small molecules targeting tumors that depend on alternative lengthening of telomeres (ALT) for their growth.
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Genome illustration

Gnomad identifies rare loss of function variants

May 29, 2020
By Nuala Moran
LONDON – A vast new body of genomics research has identified thousands of rare genetic variants that are predicted to cause loss of function in protein coding genes, providing novel in vivo models of human gene inactivation.
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Genome illustration

Gnomad identifies rare loss of function variants

May 27, 2020
By Nuala Moran
LONDON – A vast new body of genomics research has identified thousands of rare genetic variants that are predicted to cause loss of function in protein coding genes, providing novel in vivo models of human gene inactivation.
Read More

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