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BioWorld - Monday, June 15, 2026
Home » Keywords » LBL-047

Items Tagged with 'LBL-047'

ARTICLES

Concept of business partnership
Immune

Leads Biolabs joins a $1B development deal with Dianthus

Oct. 21, 2025
By Lee Landenberger
No Comments
Dianthus Therapeutics Inc. has joined the recent trend of companies licensing therapies in development from China. The company will pay as much as $1 billion to Nanjing Leads Biolabs Co. Ltd. for DNTH-212, a bifunctional BDCA2 and BAFF/APRIL inhibitor to treat autoimmune disorders. The payment comprises $30 million up front and some near-term milestones, plus an $8 million milestone for getting a phase I study underway. Leads Biolabs is in line to bring in another $962 million in milestones and royalties.
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Concept of business partnership
Immune

Leads Biolabs joins a $1B development deal with Dianthus

Oct. 20, 2025
By Lee Landenberger
No Comments
Dianthus Therapeutics Inc. has joined the recent trend of companies licensing therapies in development from China. The company will pay as much as $1 billion to Nanjing Leads Biolabs Co. Ltd. for DNTH-212, a bifunctional BDCA2 and BAFF/APRIL inhibitor to treat autoimmune disorders. The payment comprises $30 million up front and some near-term milestones, plus an $8 million milestone for getting a phase I study underway. Leads Biolabs is in line to bring in another $962 million in milestones and royalties.
Read More
Concept of business partnership

Leads Biolabs joins a $1B development deal with Dianthus

Oct. 16, 2025
By Lee Landenberger
No Comments
Dianthus Therapeutics Inc. has joined the recent trend of companies licensing therapies in development from China. The company will pay as much as $1 billion to Nanjing Leads Biolabs Co. Ltd. for DNTH-212, a bifunctional BDCA2 and BAFF/APRIL inhibitor to treat autoimmune disorders.
Read More
Immune

Leads Biolabs’ LBL-047 gains IND approval for autoimmune diseases

Sep. 22, 2025
No Comments
Nanjing Leads Biolabs Co. Ltd. has received IND approval from the FDA for LBL-047, its first autoimmune therapeutic candidate to enter the clinic.
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Drug R&D concept image.
Immune

LBL-047, an afucosylated anti-BDCA2/TACI fusion protein with extended half-life and dual immunosuppressive functions

June 19, 2024
At the recent EULAR meeting, a presentation by Nanjing Leads Biolabs Co. Ltd. covered the discovery of LBL-047, a novel bifunctional fusion protein targeting both plasmacytoid dendritic cells (pDCs) and B cells; it is being developed for the treatment of autoimmune diseases.
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