• Sign In
  • Sign Out
  • My Account
Subscribe
  • BioWorld
  • BioWorld MedTech
  • BioWorld Asia
  • BioWorld Science
  • Data Snapshots
  • Special reports
Clarivate
  • Data Snapshots
  • BioWorld
  • BioWorld MedTech
  • Infographics: Dynamic digital data analysis
  • Index insights
  • Special reports
  • Infographics: Dynamic digital data analysis
  • Trump administration impacts
  • Biopharma M&A scorecard
  • BioWorld 2024 review
  • BioWorld MedTech 2024 review
  • BioWorld Science 2024 review
  • Women's health
  • China's GLP-1 landscape
  • PFA re-energizes afib market
  • China CAR T
  • Alzheimer's disease
  • Coronavirus
  • More reports can be found here

BioWorld. Link to homepage.

Clarivate
  • BioWorld
  • BioWorld MedTech
  • BioWorld Asia
  • BioWorld Science
  • Data Snapshots
    • BioWorld
    • BioWorld MedTech
    • Infographics: Dynamic digital data analysis
    • Index insights
  • Special reports
    • Infographics: Dynamic digital data analysis
    • Trump administration impacts
    • Biopharma M&A scorecard
    • BioWorld 2024 review
    • BioWorld MedTech 2024 review
    • BioWorld Science 2024 review
    • Women's health
    • China's GLP-1 landscape
    • PFA re-energizes afib market
    • China CAR T
    • Alzheimer's disease
    • Coronavirus
    • More reports can be found here

BioWorld. Link to homepage.

  • Sign In
  • Sign Out
  • My Account
Subscribe
Home » Newsletters » BioWorld

BioWorld

Jan. 9, 2018

View Archived Issues

Ablynx vows to stay independent as it rejects $3.1B Novo Nordisk cash plus CVR offer

DUBLIN – After receiving a second rebuff, Novo Nordisk A/S has gone public on its bid to acquire nanobody pioneer Ablynx NV for almost €2.6 billion (US$3.1 billion). Read More

Regulatory front

In a step toward interoperability of electronic health records (EHRs) and the use of big health data, the U.S. Department of Health and Human Services (HHS) released the draft Trusted Exchange Framework, as required by the 21st Century Cures Act. Read More

In the clinic

Aptevo Therapeutics Inc., of Seattle, commenced patient dosing in a phase II clinical evaluation of otlertuzumab in a new indication – peripheral T-cell lymphoma (PTCL). Otlertuzumab is a monospecific antibody targeting CD37 that was built on Aptevo’s Adaptir modular protein therapeutic platform. Read More

Other news to note

TG Therapeutics Inc., of New York, and Jiangsu Hengrui Medicine Co. Ltd., of Shanghai, entered an exclusive global license deal in which TG will obtain worldwide rights, excluding Asia but including Japan, to develop Hengrui’s Bruton’s tyrosine kinase inhibitor program. Read More

Celgene launches $7B bid for Impact Biomedicines

SAN FRANCISCO – The 36th Annual J.P. Morgan Healthcare Conference started off with a bang Monday, as Celgene Corp. talked up a proposed $7 billion acquisition of San Diego-based Impact Biomedicines Inc. built around Impact’s lead candidate, the phase III JAK2 inhibitor fedratinib, a potential treatment for myelofibrosis, a rare disease of the bone marrow. Read More

More often than not, pre-existing immunity to therapeutic Cas9 proteins

Staphylococcus aureus’ role as a human pathogen may present a headache for gene editing. Looking at blood samples from human donors, researchers found that the majority of samples had pre-existing antibodies to the Cas9 from both S. aureus and Streptococcus pyogenes. Read More

As biopharma innovation accelerates, partnering follows suit

SAN FRANCISCO – Last year was a mixed bag for biopharma dealmaking, and not just by the numbers. Lofty valuations tamped down M&A, with buy-side companies also awaiting the outcome of U.S. tax reform. Oncology assets continued to rule, although first-in-class approvals actually showed a decline. Read More

Regeneron, Sanofi throw more money into partnership (x 2)

In what seems to be an eternally growing partnership, Regeneron Pharmaceuticals Inc. and Sanofi SA plan to accelerate development of two drugs already partnered under their multidrug agreements. Read More

Axovant move SAPS value; intepirdine guillotine means answerin’ for nelotanserin

Ilise Lombardo, clinical research head of Axovant Sciences Ltd., said the firm’s ongoing efforts will “certainly be informed” by the late-stage clinical work with approved pimavanserin (Nuplazid, Acadia Pharmaceuticals Inc.) as tests proceed with similarly 5HT2A-targeting nelotanserin. Read More

Sosei lands $200M to fund six Heptares’ programs, including dementia

LONDON – Sosei Group Corp. has raised $200 million in a placing to fund clinical development of proprietary assets discovered by its U.K. subsidiary, G protein-coupled receptor (GPCR) specialist Heptares Therapeutics. Read More

Apollobio, Inovio finalize deal for HPV precancers vaccine

HONG KONG – Apollobio Corp., of Beijing, has updated and finalized its development and commercialization deal with Inovio Pharmaceuticals Inc., of Plymouth Meeting, Pa., for a vaccine developed for pre-cancers caused by human papillomavirus (HPV). Read More

Financings

Alder Biopharmaceuticals Inc., of Bothell, Wash., entered a preferred stock purchase agreement with certain institutional and other accredited investors affiliated with or managed by Redmile Group LLC. Read More

Popular Stories

  • Today's news in brief

    BioWorld
    BioWorld briefs for July 11, 2025.
  • Today's news in brief

    BioWorld MedTech
    BioWorld MedTech briefs for July 11, 2025.
  • Scientific figure illustrating astrocytes and neuron synapse

    Glia 2025: Microglial crosstalk could be early Alzheimer’s targeting opportunity

    BioWorld
    “Loss of synapses and dysfunctional synapses in a region-specific way is important in Alzheimer’s. It’s actually the strongest correlate of cognitive decline, far...
  • New oral BRD4 inhibitor blocks pathogenic expansion of epithelial progenitors in IPF models

    BioWorld Science
    Idiopathic pulmonary fibrosis (IPF) is a progressive and fatal lung disease with limited treatment options. IPF is thought to result from repeated microinjuries...
  • 3D rendering of a molecular glue mediating the interaction between two proteins

    With surface mimicry, molecular glues shed hairpin need

    BioWorld Science
    Degradation is a therapeutic strategy that could offer possibilities to get at currently undruggable target proteins. In targeted degradation, compounds induce...
  • BioWorld
    • Today's news
    • Analysis and data insight
    • Clinical
    • Data Snapshots
    • Deals and M&A
    • Financings
    • Newco news
    • Opinion
    • Regulatory
    • Science
  • BioWorld MedTech
    • Today's news
    • Clinical
    • Data Snapshots
    • Deals and M&A
    • Financings
    • Newco news
    • Opinion
    • Regulatory
    • Science
  • BioWorld Asia
    • Today's news
    • Analysis and data insight
    • Australia
    • China
    • Clinical
    • Deals and M&A
    • Financings
    • Newco news
    • Regulatory
    • Science
  • BioWorld Science
    • Today's news
    • Biomarkers
    • Cancer
    • Conferences
    • Endocrine/Metabolic
    • Immune
    • Infection
    • Neurology/Psychiatric
    • Patents
  • More
    • About
    • Advertise with BioWorld
    • Archives
    • Article reprints and permissions
    • Contact us
    • Cookie policy
    • Copyright notice
    • Data methodology
    • Infographics: Dynamic digital data analysis
    • Index insights
    • Podcasts
    • Privacy policy
    • Share your news with BioWorld
    • Staff
    • Terms of use
    • Topic alerts
Follow Us

Copyright ©2025. All Rights Reserved. Design, CMS, Hosting & Web Development :: ePublishing

BioWorld. Link to homepage.

Clarivate
  • BioWorld
  • BioWorld MedTech
  • BioWorld Asia
  • BioWorld Science
  • Data Snapshots
    • BioWorld
    • BioWorld MedTech
    • Infographics: Dynamic digital data analysis
    • Index insights
  • Special reports
    • Infographics: Dynamic digital data analysis
    • Trump administration impacts
    • Biopharma M&A scorecard
    • BioWorld 2024 review
    • BioWorld MedTech 2024 review
    • BioWorld Science 2024 review
    • Women's health
    • China's GLP-1 landscape
    • PFA re-energizes afib market
    • China CAR T
    • Alzheimer's disease
    • Coronavirus
    • More reports can be found here

BioWorld. Link to homepage.

  • Sign In
  • Sign Out
  • My Account
Subscribe