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Home » Newsletters » BioWorld

BioWorld

Feb. 16, 2017

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In the clinic

Strekin AG, of Basel, Switzerland, presented preclinical data and an update on its phase II development program for STR001 at the Association for Research in Otolaryngology Conference in Baltimore. Read More

Other news to note

Trianni Inc., of San Francisco, agreed to license the use of its Trianni Mouse, a monoclonal antibody discovery platform, to Janssen Biotech Inc., a unit of Johnson & Johnson, of New Brunswick, N.J. The platform provides access to a complete human antibody repertoire optimized for the rapid isolation of fully human therapeutics. Read More

Financings

Auris Medical Holding AG, of Zug, Switzerland, priced a public offering of 10 million common shares and 10 million warrants that each entitle its holder to purchase 0.70 of a common share. Read More

Earnings

Alkermes plc, of Dublin, reported that for the year ending Dec. 31, 2016, total revenues increased 19 percent, to $745.7 million, which included net sales of $209.0 million for Vivitrol (naltrexone for extended-release injectable suspension) and net sales of $47.2 million for the schizophrenia drug, Aristada (aripiprazole lauroxil). Read More

Versant splashes cash on NASH: $20M in series A funding to Jecure

DUBLIN – Jecure Therapeutics Inc. raised $20 million in series A funding for the discovery and development of therapeutics to treat non-alcoholic steatohepatitis (NASH) and liver fibrosis, based on new insights into the sterile inflammatory processes that drive the disease. Read More

An open door for tenapanor: Phase III score by Ardelyx in ESRD, next trial shortly

Key opinion leaders (KOLs) were "giddy" about Ardelyx Inc.'s phase III data with tenapanor for hyperphosphatemia in patients with end-stage renal disease who are on dialysis, said CEO Mike Raab, and the company is putting together plans for another experiment that could lead to approval. Read More

A word from HHS could open U.S. borders to Rx drugs from Canada

Drug reimportation into the U.S. is gathering steam in Congress. But an act of Congress isn't needed to make it happen. Read More

'IVA' lot more cash: Inventiva raises $51M

DUBLIN – Inventiva SA raised €48 million ($50.9 million) in the third European biotech IPO of 2017. The Dijon, France-based drug developer priced the offer at €8.50 per share, at the bottom of the indicative range of €8.50 to €9.75 it set at the start of the bookbuilding process. Read More

Bacterial immunotherapy shows promise in tumor-targeting

A nonvirulent tumor-targeting bacterial strain bioengineered to release multiple Toll-like receptor (TLR) ligands was shown to suppress tumor growth and prolong survival in mouse tumor models in a Korean study, suggesting it could be a new cancer immunotherapy in humans. Read More

BACE1cally kaput? Merck stops Alzheimer's study for lack of efficacy

Merck & Co. Inc. is calling a halt to a high-profile phase II/III study of verubecestat after data monitors found "virtually no chance of finding a positive clinical effect" for patients with mild to moderate Alzheimer's disease. Read More

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