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Home » Newsletters » BioWorld

BioWorld

Dec. 27, 2016

View Archived Issues

Merck's Ebola vaccine 'remarkable' in final ring vaccination trial data

LONDON – The final results of the ring vaccination study of Merck & Co. Inc.'s Ebola vaccine show it to be 100 percent effective, with no one who received VSV-ZEBOV contracting the virus. Read More

Subanalysis in Asian patients yields solid data for Pfizer's Ibrance

HONG KONG – Pfizer Inc. said its FDA breakthrough-designated breast cancer drug, Ibrance (palbociclib), could have a significant impact in Asia, based on a subanalysis in Asian women from a phase III trial, showing that the combination of Ibrance and letrozole significantly extended progression-free survival (PFS) by more than 11 months compared with letrozole plus placebo. Read More

CRISPR goes massively multiplex, further expanding reach

Researchers have developed what they have termed CRISPR-enabled trackable genome engineering (CREATE), a high-throughput method to generate mutations and analyze their effects. Read More

Analysis suggests Indian pharma firms to grow through M&A

NEW DELHI – Indian pharmaceutical companies will continue to grow through acquisitions of overseas assets in the next 18 to 24 months, with the aim of deepening their geographic and product diversity and increasing their presence in developed and emerging markets, according to a recent report by Moody's Analytics. Read More

To be or not to be – in a consortium, that is

Another day, another research consortium – at least that's the way it sometimes feels early stage drug development is playing out. From Alzheimer's disease (AD) to Zika virus, the upswing in biopharma consortia is unmistakable. Read More

Financings

Oncobiologics Inc., of Cranbury, N.J., said it entered a note and warrant purchase agreement with existing investors providing for the issuance and sale of up to $10 million of senior secured promissory notes and five-year warrants to acquire an aggregate of 2.3 million shares of company stock at an exercise price of $3 each. Read More

Other news to note

Aerie Pharmaceuticals Inc., of Irvine, Calif., said its third-party manufacturing vendor for Rhopressa (netarsudil ophthalmic solution) 0.02 percent will not be ready for pre-approval inspection by the FDA until the end of February 2017. Read More

Holiday Notice

BioWorld's offices were closed Monday, Dec. 26, in observance of the Christmas Day holiday. Read More

Appointments and advancements

Surface Oncology Inc., of Cambridge, Mass., named Robert W. Ross chief medical officer. Read More

In the clinic

Cel-Sci Corp., of Vienna, Va., in an 8-K filing reported that although it believed the response submitted to the FDA in November addressed each of the deficiencies identified by the agency and outlined in a partial clinical hold letter, the FDA issued an incomplete response to the hold letter. Read More

Bench Press: BioWorld looks at translational medicine

Researchers from The Scripps Research Institute and Harvard Medical School have identified Piezo2 as a stretch receptor in the lungs with important roles both in initiating normal breathing at birth and maintaining it in adulthood. Read More

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