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Home » Newsletters » BioWorld

BioWorld

April 21, 2020

View Archived Issues
Coronavirus-pandemic2

Manhattan Project approach to COVID-19 could change drug development

The urgent need to have at least a few proven COVID-19 therapies approved in the U.S. before the pandemic’s expected resurgence in the fall has become biopharma’s Manhattan Project – a coming together of industry, researchers and government agencies to take on a single global enemy. Read More

Cyclacel, Pharming repurpose drugs to fight severe respiratory symptoms of COVID-19

LONDON – The search for modulators of the immune cascade that is the cause of the most severe respiratory symptoms of COVID-19 is intensifying, with Cyclacel Pharmaceuticals Inc. and Pharming Group NV adding their drugs to the list of repurposing projects. Read More
Illustration of brain, DNA

Investors still tracking companies developing therapies for cancer, neurological diseases

Although the product pipeline for vaccines and therapeutics targeting COVID-19 is top of mind right now, investors are also keeping a close eye on companies involved in the development of medicines targeting cancer and the central nervous system. According to financings tracked by BioWorld and deals and grants logged in Cortellis, the therapeutic areas of cancer, neurology and psychiatric attracted the highest amounts of investments last year with a collective $101.9 billion and $27.5 billion raised, respectively. Read More

Cara package delivers investor relief, Korsuva filing in second half

Despite the higher placebo response than a previous, identically designed experiment turned up, Cara Therapeutics Inc.’s Kalm-2 phase III study Korsuva (CR-845/difelikefalin) for injection handily reached its primary endpoint in hemodialysis patients with moderate to severe chronic kidney disease-associated pruritus (CKD-aP). Read More
Swiss biotech

Swiss biotech investment slipped 25% in 2019 as sector braced for COVID-19 disruption

DUBLIN – The Swiss biotech sector raised about CHF1.2 billion ($$1.2 billion) in equity investment in 2019, a significant downward dip on the last two years, but well ahead of its average annual raise of CHF800 million over the past decade, according to the newly published Swiss Biotech Report 2020. Read More

Memgen, Moffitt licensing deal centers on tumor targeting candidate

Privately held Memgen LLC and the H. Lee Moffitt Cancer Center agreed to technology licensing agreements covering intellectual property the two jointly developed. The deal includes MEM-288, Memgen’s lead candidate, which the company said exhibits significantly enhanced selectivity and activity against a range of tumor types. Read More

Scynexis sees path for antifungal asset approval with new pivotal data

New pivotal data on Scynexis Inc.'s lead candidate, an antifungal for vulvovaginal candidiasis (VVC), have cleared the path to an NDA filing in the indication later this year and a potential approval in mid-2021. Read More
australia-coronavirus-covid-19.png

Australia’s biotech sector tests multiple agents to fight COVID-19

PERTH, Australia – The Australian Government is providing AU$13 million (US$8 million) to fast-track research into treatments for COVID-19, and a number of promising candidates are about to enter the clinic. Read More

Appointments and advancements for April 21, 2020

New hires and promotions in the biopharma industry, including: Abeona, ADC, Adverum, Applied Molecular Transport, Arch, Cocrystal, Geneuro, Hemostemix, Kineta, Nellone, Oculis, Outlook, Rockwell, Sangamo. Read More

In the clinic for April 21, 2020

Clinical updates, including trial initiations, enrollment status and data readouts and publications: Applied Therapeutics, Arcutis, Atyr, Cara, Catalyst, CSL Behring, Erytech, Hookipa, Idera, Novartis, Oncoimmune, Synexis. Read More

Other news to note for April 21, 2020

Biopharma happenings, including deals and partnerships, grants, preclinical data and other news in brief: Acerus, Adamis, Aikido, Allterum, Bayer, Biogen, Biosig, Cipher, Edesa, Forma, Galephar, Innovation, Merck, Mogrify, Novan, Novimmune, Opgen, Pharming, Polarityte, Redhill, Revive Therapeutics, Sangamo, Sun, Suono Bio, Twoxar Pharmaceuticals, Upsher-Smith, Vaxart, VBL, Viravaxx, Vivacelle. Read More

Regulatory actions for April 21, 2020

Regulatory snapshots, including global drug submissions and approvals, clinical trial approvals and other regulatory decisions and designations: Alk-Abello, Bayer, Beigene, Boehringer Ingelheim, Hope, Myovant, Passage. Read More

Regulatory front for April 21, 2020

The latest global regulatory news, changes and updates affecting biopharma. Read More

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