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Home » Newsletters » BioWorld

BioWorld

Feb. 17, 2022

View Archived Issues
Single strand ribonucleic acid

Remix RNA modulators draw $45M backing from Janssen for immunology, oncology targets

Remix Therapeutics Inc., a company developing small molecules to manipulate RNA processing, stands to earn upward of $1 billion through a new strategic collaboration with Janssen Pharmaceutica NV. A Cambridge, Mass.-based startup, Remix last year patented new RNA splicing modulators. It will receive an initial payment of $45 million for research funding plus potential preclinical, clinical, commercial and sales milestone payments, and royalties. Janssen gains exclusive rights to three targets with applications in immunology and oncology. Read More

Marker’s phase II data and pipeline expansion prompt market wobble

Marker Therapeutics Inc.’s update from the safety lead-in stage of its phase II study of MT-401 in treating post-transplant acute myeloid leukemia saw response in one of the six participants. The results from the study of the multitumor-associated antigen-specific T-cell product also known as zelenoleucel saw firms such as Oppenheimer cut its target price for Marker to $5 from $8 and Piper Sandler to cut its target price from $5.50 to $4. Read More
Oral medication

Modra eyes pivotal trial of docetaxel pill after supportive findings in prostate cancer

Modra Pharmaceuticals BV is planning to move its oral formulation of docetaxel into a pivotal trial, hoping to offer advanced prostate cancer patients a safer treatment option than intravenous chemotherapy. The Amsterdam, the Netherlands-based company has just announced phase IIb results in metastatic castration-resistant prostate cancer from ModraDoc-006/r, a tablet containing docetaxel and co-administered with ritonavir to enhance bioavailability. Read More
Francis Collins, director, NIH

Collins temporarily assigned new scientific role in US government

As the Biden administration continues to play musical chairs with key U.S. federal health leadership positions, its latest move is naming Francis Collins to serve as science adviser to the president and co-chair of the President’s Council of Advisers on Science and Technology. Read More
Leukemia illustration

Bluesphere emerges from stealth with search and capture TCR platform

Before taking on the role of CEO at Bluesphere Bio Inc., David Apelian would have said the most exciting work he’d done in immuno-oncology had been at Globeimmune Inc., where he’d served as chief medical officer for more than a decade, working in the field of cancer immunotherapy “back when no one believed the immune system would be something we could leverage against cancer.” Read More
US flag, Department of Health and Human Services flags

Court: US HHS violation letters violative

Drug companies won another round in their battle with the U.S. Department of Health and Human Services (HHS) over how many contract pharmacies must be given the steep discounts dictated under the 340B drug pricing program aimed at helping public clinics and hospitals provide charity care. Read More
asia-india-flag

India’s health care industries receive mixed messages from authorities

India’s health care industry stakeholders have been left scratching their head as authorities, who have championed self-reliance and increased supplies, provided mixed signals in recent notices. Read More

BioWorld Insider Podcast: Could long COVID be the next public health crisis?

With the study of long COVID-19 continuing to evolve, the BioWorld team is taking a closer look at the condition – a complex syndrome affecting more than 100 million people globally – and what's being done about it. In this episode, BioWorld Senior Science Editor Anette Breindl and Staff Writer Lee Landenberger, fresh off writing a pair of detailed stories about these issues, join us to talk about how consensus around what long COVID is has emerged.


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Appointments and advancements for Feb. 17, 2022

New hires and promotions in the biopharma industry, including: AI Therapeutics, Avalo, Canbridge, Leo, Longeveron, Lyra. Read More

Financings for Feb. 17, 2022

Biopharmas raising money in public or private financings, including: Sunshine. Read More

In the clinic for Feb. 17, 2022

Clinical updates, including trial initiations, enrollment status and data readouts and publications: Biogen, BMS, Rhythm, Sage, Theratechnologies.

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Other news to note for Feb. 17, 2022

Biopharma happenings, including deals and partnerships, grants, preclinical data and other news in brief: Applied DNA Sciences, Aridis, Biontech, Catalyst, Davita Clinical Research, Enveric, Evvivax, Insilico Medicine, Intervivo Solutions, Johnson & Johnson, Mediwound, Mindset, Neopharm, Neumora, Partner, Pfizer, Quoin, Repertoire, Shanghai Fosun, Yumanity. Read More

Regulatory actions for Feb. 17, 2022

Regulatory snapshots, including global drug submissions and approvals, clinical trial approvals and other regulatory decisions and designations: Acadia, Avenue, Biontech, Celcuity, GBT, Hemogenyx, Hillstream, Jixing, Lexeo, Mirati, Moderna, Pfizer, Revive, Sirnaomics, Swanbio. Read More

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