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Home » Newsletters » BioWorld

BioWorld

Nov. 30, 2022

View Archived Issues
Neurons and amyloid plaques

Amyloid plaques recast as cause of neural network dysfunction

Researchers have identified a link between amyloid plaques and dysfunctional neuronal conduction in animal models of Alzheimer’s disease (AD). Their study, which was published in the Dec. 1, 2022, issue of Nature, suggests new ways to think about AD, as well as badly needed potential alternatives to plaque removal to fight the disease. Read More

More clarity on lecanemab as Eisai and Biogen present trial data

Eisai Co. Ltd. and Biogen Inc. presented the full data set for the Clarity Alzheimer’s disease trial of lecanemab at the 2022 Clinical Trials on Alzheimer’s Disease, which was simultaneously published in the New England Journal of Medicine. The data supported the top-line results released in September 2022. Read More
Merger-chess-piece.png

Horizon sees interest from trio of big pharma suitors

Horizon Therapeutics plc shares (NASDAQ:HZNP) jumped 27.3% to $100.29 after the company disclosed being in "highly preliminary" discussions about takeover interests expressed by Amgen Inc., Janssen Global Services LLC and Sanofi SA. The companies have until Jan. 10, 2023, to report whether they intend to make an offer or not. Read More

Inhibrx glitch in phase I foregrounds chondrosarcoma push

Wall Street’s reaction to phase I news in chondrosarcoma from Inhibrx Inc. puzzled some onlookers and brought renewed attention to the rare disease, which is also the most common form of primary bone cancer in adults. Big pharma and smaller concerns have been throwing drug prospects at the condition for years without much luck. Read More
Lab glassware and scientist

Ryvu small-molecule smarts pull in $41M down payment from Biontech

Ryvu Therapeutics SA is banking €40 million (US$41.3 million) as an initial payment from a two-pronged alliance with Biontech SE, which involves a multitarget small-molecule research collaboration in immunotherapy and a license agreement for Ryvu’s portfolio of Sting agonists. Read More

PIE Act reintroduced in US House of Representatives

The U.S. House of Representatives has resurrected the Pre-approval Information Exchange (PIE) Act, a bill that would bolster the prospects for drugs and devices by improving communications with payers prior to U.S. FDA clearance or approval of the product. Read More

Appointments and advancements for Nov. 30, 2022

New hires and promotions in the biopharma industry, including: Aeglea, Anaveon, Aurion, Centessa, Chemomab, NXI, Pathios, Terray. Read More

Financings for Nov. 30, 2022

Biopharmas raising money in public or private financings, including: Acer, Iecure, Nectin, Oncosec, Re-Vana, TFF. Read More

In the clinic for Nov. 30, 2022

Clinical updates, including trial initiations, enrollment status and data readouts and publications: Atea, Biovie, Hansa, Inversago, Mebias, Mirum, Netris, Tyra. Read More

Other news to note for Nov. 30, 2022

Biopharma happenings, including deals and partnerships, grants, preclinical data and other news in brief: Akous, Argenx, Bluebird Bio, Boehringer Ingelheim, Eli Lilly, Erasca, Horizon, Immutep, Legochem, Merck, Pfizer, Pierre Fabre, Ribon, Sotio, Turnstone, Vergent, Zymeworks. Read More

Regulatory actions for Nov. 30, 2022

Regulatory snapshots, including global drug submissions and approvals, clinical trial approvals and other regulatory decisions and designations: Aldeyra, Ascletis, Buchang, Capstone, Caribou, Genentech, Gilead, Kala, Novavax, Remd, Sofie. Read More

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