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Home » Newsletters » BioWorld

BioWorld

Feb. 26, 2025

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A DNA double helix rests on a print-out illustration of the DNA  base pair letters A, T, C and G.

UK research effort finds 141 new rare disease-gene associations

Whole genome sequencing has substantially accelerated the pace of discovery of genes that cause rare diseases, but while this has brought the diagnostic odyssey of some patients to a conclusion, 50% to 80% remain undiagnosed after initial analysis. Read More

Bipartisan PBM reforms back on the congressional table

The U.S. Congress is turning its attention, once again, to bipartisan pharmacy benefit manager (PBM) reforms, after efforts to rein in PBM practices died with the 118th Congress. With an eye on finally getting them passed, the House Energy and Commerce Committee kicked off the process with a Feb. 26 hearing that was supposed to be focused on the reform legislation the committee approved last year and follow-on legislation to rein in harmful PBM practices. Read More
Alfred Bowie, chief financial officer, Eikon

Eikon tops the year’s VC rounds as it enters a phase III in cancer

With the closing of its $350.7 million series D, Eikon Therapeutics Inc. has notched two financial high marks for the still young year. The funding is the biggest venture capital round of 2025 and it’s also the first series D. Read More
Biocom AI panel

Biocom 2025: The quickly evolving AI landscape

A panel at Biocom California’s 15th Annual Global Life Science Partnering & Investor Conference covered the emerging use of artificial intelligence (AI) to discover and develop drugs. “We’re in a very different place than we were five years ago, or even three years ago, even two years ago, from our ability to harness AI to make advances,” Marc Tessier-Lavigne, CEO of South San Francisco-based Xaira Therapeutics Inc., told the audience, adding that the development is actually accelerating. Read More
Deal-handshake-wire-frame.png

Harbour Biomed newco HBM Alpha pens $395M hyperplasia drug deal

HBM Alpha Therapeutics Inc. signed a potential $395 million licensing deal Feb. 26 with an unnamed “business partner” for its endocrine asset, HAT-001, adding another contender to the congenital adrenal hyperplasia space. Read More

Biocity’s SC-0062 hits phase II endpoints in diabetic kidney disease

Biocity Biopharmaceutics Co. Ltd.’s selective endothelin receptor type A antagonist, SC-0062, met the primary endpoint of reducing proteinuria in a phase II diabetic kidney disease cohort. Conducted at 40 sites across China, the 2-Succeed phase II trial is designed to evaluate the efficacy and safety of SC-0062 in patients with chronic kidney disease with proteinuria. Read More

BioWorld Insider Podcast: Mega money well spent? Mammoth mergers fall short of the dream

Billion-dollar M&As are commonplace now, but not too long ago they were a rarity. So many have occurred in the past few years, they’ve become the norm. But were all these multi-billion-dollar mega mergers worth the money? Karen Carey, BioWorld’s senior managing editor and chief analyst, crunched the numbers on 21 of the biggest M&As in a three-part BioWorld series and found very few have been, so far, good deals for the buyer. In this podcast, Carey sifts through the winners and losers and explains the analysis. Read More
World trade illustration

Five med-tech trends to watch in 2025

The Clarivate Medtech Trends to Watch in 2024 report noted the resilience of the medtech sector in the face of changing macroeconomic factors and the preparation required to navigate the market’s many complexities. It is likely that 2025 will be no different. Read More

Appointments and advancements for Feb. 26, 2025

New hires and promotions in the biopharma industry, including: Aim Immunotech, Aspargo Laboratories, Evotec, Forx, Omass, Realta. Read More

Financings for Feb. 26, 2025

Biopharmas raising money in public or private financings, including: Financings: Castle Creek, GT, Ligand, Maia, Paradox. Read More

Other news to note for Feb. 26, 2025

Biopharma happenings, including deals and partnerships, grants, preclinical data and other news in brief: Carsgen, Eli Lilly, Hyloris, Infex, Kiniksa, Lava, Nimbus, Oncopeptides, Organovo, Redhill, Ucarsgen, Venus. Read More

In the clinic for Feb. 26, 2025

Clinical updates, including trial initiations, enrollment status and data readouts and publications: Elixirgen, Eupraxia, Medicenna, Regeneron, Terns, Yoltech. Read More

Regulatory actions for Feb. 26, 2025

Regulatory snapshots, including global drug submissions and approvals, clinical trial approvals and other regulatory decisions and designations: Formycon, Grin, Hyloris, Kashiv, Merck & Co., Mirum, Precigen, Sanofi. Read More

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