Ablynx NV raised €31.5 million (US$41 million) in a private placement, boosting cash reserves to around €90 million and allowing the company to progress development of its next-generation rheumatoid arthritis (RA) product ALX-0061 into Phase IIb, while negotiating with potential partners.
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A new genetic study has provided backing for the theory that inflammation in the brain is a cause of psychosis. Researchers in Sweden have discovered that a genetic variant that boosts the effects of inflammation in the brain is more common in people with bipolar disorder who experience psychotic episodes.
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The European Commission (EC) finally put some financial firepower behind its pledge to find treatments for 200 rare diseases by 2020, announcing €144 million (US$187 million) of new funding for 26 separate projects.
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Privately held Concert Pharmaceuticals Inc. struck another business development high note, inking an exclusive license agreement that provides Jazz Pharmaceuticals plc with global rights to develop and commercialize deuterium-modified sodium oxybate (D-SXB) compounds, including C-10323, aimed at narcolepsy.
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• Polyphor Ltd., of Allschwil, Switzerland, completed a Phase I trial demonstrating the clinical safety and tolerability of its Pseudomonas-specific antibiotic POL7080.
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