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BioWorld Science

April 28, 2006

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Phase II studies show notable activity of sunitinib in metastatic renal cell carcinoma

NOX-F37: a Spiegelmer that targets AVP to evoke diuresis

Safetek to develop new selective muscarinic receptor antagonist for OAB

Isotechnika signs option agreement for topical delivery of ISA-247

Stem Cell Therapeutics enters agreement to support phase IIa study of NTx-265

Enrollment completed in confirmatory study of OrCel in venous leg ulcers

FivePrime and Boehringer Ingelheim team up in rheumatoid arthritis

Activity of phenserine tartate in Alzheimer's disease detailed in clinical trials

FAS-93: FAS-targeting antineoplastic strategy without associated anorexia

Phase I data presented on SLV-317

E.U. label change for Intron

First approvals for initiation of PrimoVax study of GV-1001

SPARC trial of satraplatin cleared to continue to completion

Novel MEK inhibitor ARRY-438162 begins phase I study

Orphan drug designation for Nexavar in hepatocellular carcinoma

New phase III study for AIR Inhaled Insulin System

Orathecin study fails to meet median survival threshold for advancement

Exforge NDA accepted for review

Japanese approval for lanoconazole for athlete's foot

New nuclear export inhibitor displays antitumor efficacy and a favorable therapeutic index

In vitro and in vivo profiling of GW-427353, a beta-3 adrenergic agonist clinical candidate

Cimzia MAA submitted in Europe for Crohn's disease

NDA submission for single-tablet regimen of Sustiva and Truvada

European CHMP hands down positive opinion for Nexavar in kidney cancer

Valeant discloses new therapeutic agents for HIV infection

New treatments for cancer covered in recent patents

Herceptin recommended for approval for early-stage breast cancer in Europe

U.K. approval for DepoDur in postoperative pain

New antiinfective agents the subject of recent patents

Epothilones with favorable pharmacological profiles a highlight at the AACR meeting

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