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BioWorld Science

May 16, 2006

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Decitabine effective in phase III study in myelodysplastic syndromes

Eugenol: a phytochemical with in vivo antihyperalgesic efficacy

New product and pipeline developments at Shire

Roche profiles pipeline progress

Vertex reports steady progress in multiple programs

The alpha2delta1 subunit of the VGCC: a drug target for neuropathic pain / News in Context

Anti-hepatitis C activity of NIM-811 demonstrated in vivo

T-22 enhances cyclophosphamide efficacy against lung metastases

AFG BioSolutions to study Multiferon against biological threats

Callisto enters sponsored research agreement with M.D. Anderson for degrasyns

Phase I data on siRNA for RSV / News in Context

EpiStem to conduct preclinical testing for Callisto's guanilib

AC-03-636 prolongs survival of rats with experimental gliomas

SPA for phase III study of TroVax in renal cell carcinoma

Lexicon Genetics receives grant for target identification in spinal muscular atrophy

Preliminary safety analyses from off-drug follow-up in APPROVe Vioxx study

Intercell and Merck form antibody alliance for S. aureus infections

Threshold changes TH-070 development program

Gedeon Richter signs new agreement for antipsychotic RGH-188

PMA submission for Cypher stent for in-stent restenosis

PTC-299 begins phase Ia study

Novel small-molecule inhibitor of CRP to prevent complement-mediated exacerbation of infarct injury

Novel p38alpha mitogen-activated protein kinase inhibitors claimed in recent Pfizer patent

Barbeau Pharma prepares and tests novel dopamine D2 receptor antagonists

Recent patents disclose novel treatments for gastrointestinal diseases

Novel series of quinazolin-4(3h)-one derivatives with antiviral activity reported

Novel compounds with activity against H5N1 avian influenza virus synthesized

Chimeric compound with antioxidant and calpain inhibitor activity improves MD symptoms

Absence of corneal toxicity suggests naltrexone may be useful for diabetic keratopathy

Snapshots on genetically engineered therapeutic strategies for choroidal neovascularization

Taxus Liberte stent system approved in E.U. for additional coronary procedures

Keppra approved by E.C. as adjunctive therapy for myoclonic seizures in patients with JME

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